I’m not diabetic and the situation with insulin fills me with a white hot rage.
Insulin
Submitted 6 hours ago by fossilesque@mander.xyz to science_memes@mander.xyz
https://mander.xyz/pictrs/image/216fcb24-3a25-42f9-aaa4-c2d9699530bd.png
Comments
Wild_Mastic@lemmy.world 5 hours ago
Meanwhile, 10 euros per vial here in Europe. At least his original plan for widespread and easy availability has partially succeeded.
neukenindekeuken@sh.itjust.works 4 hours ago
In civilized countries at least.
ChilledPeppers@lemmy.dbzer0.com 3 hours ago
In brazil 36 reais (about 6 euro). The US is a joke. (And im 99% sure you can also get it for free if you use the public health network)
mika_mika@lemmy.world 1 hour ago
I have mental health disabilities in the USA and my meds are at zero cost because I literally have had absolute zero income for the past 5 years.
You wouldn’t believe how much those mood stabilizer/antidepressant cocktails stack up proportionally when I was able to scrape by on $15 an hour.
The system set me up to fail with how shitty it is, if healthcare wasn’t crap I could be contributing to society without crippling myself.
BootLoop@sh.itjust.works 5 hours ago
Canadians: invented drug and patent it freely Americans: Finds way to kill the most people possible while making the most amount of money
Phil_in_here@lemmy.ca 5 hours ago
To be fair, the killing isn’t the point; they’re the product. Its just that profit is God, so killing in its name is justified.
Killing poors for the joy of it? That’s just an evil bonus.
jaybone@lemmy.zip 3 hours ago
Killing me soupy with his words.
macncheese@lemmy.world 4 hours ago
California is contracting its own insulin supply and it’ll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We’re in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. chhs.ca.gov/…/governor-newsom-announces-affordabl…
fullsquare@awful.systems 10 minutes ago
I know not every state can or are willing to do this
this kind of thing scales well, i see no reason why after california has it set up, other states couldn’t get insulin from them, or chip in
LibertyLizard@slrpnk.net 2 hours ago
Seems like something other states should get in on. Now that the program is established seems like it would not be as hard to pay into it and get a share of the product.
wurstgulasch3000@feddit.org 1 hour ago
But that’s socialism! /s
Zacryon@feddit.org 3 hours ago
Naive question from a european: Aren’t there companies on the market who can offer a cheaper price and therefore beat greedy competitors?
fullsquare@awful.systems 1 hour ago
also european, but with some background: the problem is that there is natural (as in, unmodified) generic insulin available, it’s just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time, you don’t want to do that, you’d like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can’t reach it. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure
for another example, ozempic was not the first drug in its class, it’s also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it’s only two minutes (it gets released a bit slower than it is metabolized)
Sir_Premiumhengst@lemmy.world 1 hour ago
Oh wow, an actual nuanced response and genuine answer!
Also today I learned!
Soulg@ani.social 2 hours ago
Correct, but when it’s already been established that people will pay those prices, they keep them high. So instead of going from $800 to $5 out of the goodness of their hearts, they go from $800 to $650 (number made up) to get more business but still make massive profits.
Lumidaub@feddit.org 3 hours ago
You’d THINK capitalism would cause that to happen, wouldn’t you?
Banana@sh.itjust.works 2 hours ago
Doesn’t work when people don’t get to choose not to take it when it gets too expensive! That thing that capitalists always forget about: necessities.
Kaput@lemmy.world 1 hour ago
What USA is experiencing is feral Capitalism.
hakase@lemmy.zip 3 hours ago
Yup, but their products don’t work as well, don’t work for everyone, or have other downsides. Banting’s original insulin would be dirt cheap today, but it’s shit compared to what we have now, so the best products on the market today charge a premium for either efficacy or convenience.
TheLeadenSea@sh.itjust.works 6 hours ago
I wondered if all the sane Americans did a max exodus to Canada, Europe, UK, Australia etc, what effect that wound have
PunnyName@lemmy.world 5 hours ago
A lot of us would need financial sponsorship. So there’d be a literal financial drain on those economies.
I still would like to sign up.
Soup@lemmy.world 5 hours ago
Not if you stayed, then it’s an investment. Money doesn’t just disappear when goes to poor people, they use it to buy things like food and stuff. It would only be a financial drain if you were sending that money back home.
The North American mind cannot comprehend the benefits of supporting the poor.
turdcollector69@lemmy.world 2 hours ago
It’s already happening, there’s been a deluge of affluent people leaving the US.
We’re still at the stage where it takes considerable privilege to just leave everything behind and pay the exit extortion (40% of all your shit).
Once things get worse and people have nothing to leave behind you’ll start seeing the engineers/doctors escaping.
pennomi@lemmy.world 5 hours ago
Have you looked into what it takes to get a permanent visa to one of those countries? It’s not easy.
Master@sh.itjust.works 5 hours ago
Its prohibitively impossible.
Fizz@lemmy.nz 3 hours ago
Its not that hard especially for an American.
fossilesque@mander.xyz 5 hours ago
I did it a while ago, would recommend.
PM_ME_VINTAGE_30S@lemmy.sdf.org 25 minutes ago
If you don’t mind sharing, did you have to pay the exit tax? Actually, what was your way out?
Redkid1324@lemmy.world 5 hours ago
Aren’t you still paying taxes to the USA? Just curious.
ininewcrow@lemmy.ca 5 hours ago
Americans suffer from Stockholm syndrome
PM_ME_VINTAGE_30S@lemmy.sdf.org 5 hours ago
Reminder that the term Stockholm Syndrome was coined to blame victims for being rightly more afraid of the police than their captors:
In [Jess Hill’s] 2019 treatise on domestic violence See What You Made Me Do, Australian journalist Jess Hill described the syndrome as a “dubious pathology with no diagnostic criteria”, and stated that it is “riddled with misogyny and founded on a lie”; she also noted that a 2008 literature review revealed “most diagnoses [of Stockholm syndrome] are made by the media, not by psychologists or psychiatrists.” In particular, Hill’s analysis revealed that Stockholm authorities, responded to the robbery in a way that put the hostages at greater risk from the police than from their captors (hostage Kristin Enmark, who during the siege was granted a telephone call with Swedish Prime Minister Olof Palme, reported that Palme told her that the government would not negotiate with criminals); as well, she observed that Bejerot’s diagnosis of Enmark was made without ever having spoken to her.
ozymandias@lemmy.dbzer0.com 5 hours ago
AmeriKKKans
whoa! so edgy, poignant, and relevant!
and so creative!
amazing!
and everyone clappedQuinnyCoded@sh.itjust.works 5 hours ago
Stockholm syndrome is a proposed condition to explain why hostages occasionally develop a psychological bond with their captors. It is named after an attempted bank robbery in 1973, in Stockholm, Sweden
?
mirshafie@europe.pub 4 hours ago
Nils Bejerot was a total hack. He tried to ban comic books, and later transcribed that same energy in a war on drugs that has resulted in some of the worst health outcomes for drug users in Europe. Unfortunately his ability to be confidently incorrect swayed a lot of gullible rubes, and his legacy still casts a shadow over Sweden to this day.
ameancow@lemmy.world 4 hours ago
I would literally move if I could afford it and if it was even a little easier.
Stockholm syndrome suggests we enjoy it or want to be here.
Elgenzay@lemmy.ml 4 hours ago
PM_ME_VINTAGE_30S@lemmy.sdf.org 4 hours ago
Does anyone really need to live? What you need is to be producing value for your company!
/S
Elgenzay@lemmy.ml 3 hours ago
Also I just remembered, I used to have United Healthcare and they didn’t cover this medicine so I had to switch. Had to pay ~$300 for that refill (i think it was fewer tablets and 75mg that time). $40 on my current insurance.
Anyway I’m a big Luigi fan
JoShmoe@ani.social 5 hours ago
I summon, Luigi!
SpaceNoodle@lemmy.world 5 hours ago
My name’s not Luigi
What are you summoning
JoShmoe@ani.social 5 hours ago
grunts Damn thing isn’t working.
greedytacothief@lemmy.dbzer0.com 4 hours ago
If I’m remembering the original sysntesis for insulin used dogs, and it was harvest from them after being killed. It’s unjust that insulin is so expensive, but also modern production methods are not the problem here. It’s greed.
lmmarsano@lemmynsfw.com 3 hours ago
:::spoiler Needs text alternative. Images of text break much that text alternatives do not. Losses due to image of text lacking alternative such as link:
- usability
- we can’t quote the text without pointless bullshit like retyping it or OCR
- text search is unavailable
- the system can’t
- reflow text to varied screen sizes
- vary presentation (size, contrast)
- vary modality (audio, braille)
- accessibility
- lacks semantic structure (tags for titles, heading levels, sections, paragraphs, lists, emphasis, code, links, accessibility features, etc)
- some users can’t read this due to lack of alt text
- users can’t adapt the text for dyslexia or vision impairments
- systems can’t read the text to them or send it to braille devices
- web connectivity
- we have to do failure-prone bullshit to find the original source
- we can’t explore wider context of the original message
- authenticity: we don’t know the image hasn’t been tampered
- searchability: the “text” isn’t indexable by search engine in a meaningful way
- fault tolerance: no text fallback if
- image breaks
- image host is geoblocked due to insane regulations.
Contrary to age & humble appearance, text is an advanced technology that provides all these capabilities absent from images. ::: Did they try looking for discounts from patient assistance programs from the manufacturer? They’ll reduce the cost $35.
Manufacturers try to shakedown insurance companies for obscene pay without affecting the amount individuals pay, so they offer those programs directly to individuals. Not saying this good, just how the system works.
- usability
lugal@lemmy.dbzer0.com 5 hours ago
I really don’t get it. If it was in the freezer, why will it be damaged when put back again? Is it that once defreezed some reaction goes on and shouldn’t be stopped? I really don’t get it. Would it be better to keep it outside the freezer once it warm up?
fullsquare@awful.systems 18 minutes ago
it might just be in glass vial and freezing broke it
Album@lemmy.ca 5 hours ago
It degrades from the freezing process and then dosage becomes unpredictable and thus dangerous. If you have insulin it’s got big words on it saying don’t.
Heres the side of some humalog:
DO NOT FREEZE. Store refrigerated at 36°F to 46°F [2°C to 8°C] until time of use. Store in-use vials refrigerated at 36°F to 46°F [2° C to 8°C]. If refrigeration is not possible, store at room temperature (up to 86°F [30°C]). Protect from direct heat and light.
TeamAssimilation@infosec.pub 5 hours ago
I’m sure an experienced medic in an emergency could work with it somehow, but for the rest of us living in civilization, insulin that has been outside their recommended temperature range is very dangerous.
Long-acting insulin has crystals that dissolve at body temperature over time, hence it can gradually release insulin over hours. If you break or dissolve those crystals by freezing/thawing/overwarming, the best scenario would be that it became fast-acting insulin, and it would crash your glucose instantly on injection of your usual dose. The worst scenario is that it no longer acts like insulin.
Brunbrun6766@lemmy.world 5 hours ago
Freezing temps breaks down insulin and causes it to lose efficacy which less efficacy is something you don’t want with something that keeps you alive
Daze@sh.itjust.works 5 hours ago
Methinks you read it wrong friend; it was stored in the fridge originally
lib1@hexbear.net 4 hours ago
Endogenous human insulin is stable up to five freeze-thaw cycles. However, various types of synthetic insulin become less potent once they’ve been frozen. It functionally becomes impossible to know how much insulin you need to compensate for the food you’re eating
Diddlydee@feddit.uk 5 hours ago
It was in the fridge, then put in the freezer.
tlekiteki@lemmy.dbzer0.com 5 hours ago
rea bra
dohpaz42@lemmy.world 5 hours ago
TropicalDingdong@lemmy.world 4 hours ago
cassandrafatigue@lemmy.dbzer0.com 4 hours ago
When you kill the wealthy and their enforcers, you should be shouting “blood for blood”.
ameancow@lemmy.world 4 hours ago
Since we’re roleplaying you should also say “skulls for the skull throne.”
cassandrafatigue@lemmy.dbzer0.com 3 hours ago
No. They kill us. They murder people. Make it clear why this is happening, why any negotiation starts with every billionaire shot in the gut and left to bleed out, as a compromise.
psycho_driver@lemmy.world 3 hours ago
Stanford has managed to cure type 1 diabetes in mice. Lets see if big pharma lets that get anywhere.
phoenixz@lemmy.ca 1 hour ago
If you talk about killing the few people like these that are the root cause of all these problems, you’re a terrorist. You go to jail
These people actually kill people by the thousands, millions, and we call them smart CEO’s and celebrate them 🥂
electric_nan@lemmy.ml 28 minutes ago
Free Luigi.