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Insulin

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Submitted ⁨⁨4⁩ ⁨months⁩ ago⁩ by ⁨fossilesque@mander.xyz⁩ to ⁨science_memes@mander.xyz⁩

https://mander.xyz/pictrs/image/216fcb24-3a25-42f9-aaa4-c2d9699530bd.png

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Comments

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  • psycho_driver@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Stanford has managed to cure type 1 diabetes in mice. Lets see if big pharma lets that get anywhere.

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    • fullsquare@awful.systems ⁨4⁩ ⁨months⁩ ago

      90% of drug candidates fail in clinical trials

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  • Elgenzay@lemmy.ml ⁨4⁩ ⁨months⁩ ago

    Shoutout to the uninsured cost of the medication I need to live

    Image

    (90 tablets)

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    • PM_ME_VINTAGE_30S@lemmy.sdf.org ⁨4⁩ ⁨months⁩ ago

      Does anyone really need to live? What you need is to be producing value for your company!

      /S

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      • Digit@lemmy.wtf ⁨4⁩ ⁨months⁩ ago

        A patient cured, a customer lost. A dead customer, just a cost of business.

        ^ Say “for profit medicine” (oxymoron btw), behind closed doors.

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      • Elgenzay@lemmy.ml ⁨4⁩ ⁨months⁩ ago

        Also I just remembered, I used to have United Healthcare and they didn’t cover this medicine so I had to switch. Had to pay ~$300 for that refill (i think it was fewer tablets and 75mg that time). $40 on my current insurance.

        Anyway I’m a big Luigi fan

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  • macncheese@lemmy.world ⁨4⁩ ⁨months⁩ ago

    California is contracting its own insulin supply and it’ll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We’re in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. chhs.ca.gov/…/governor-newsom-announces-affordabl…

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    • ronigami@lemmy.world ⁨4⁩ ⁨months⁩ ago

      contracting is an interesting choice of word since it could mean decreasing

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      • macncheese@lemmy.world ⁨4⁩ ⁨months⁩ ago

        That’s called a homophone.

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    • fullsquare@awful.systems ⁨4⁩ ⁨months⁩ ago

      I know not every state can or are willing to do this

      this kind of thing scales well, i see no reason why after california has it set up, other states couldn’t get insulin from them, or chip in

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      • JayGray91@piefed.social ⁨4⁩ ⁨months⁩ ago

        I would think Big Pharma will aggressively fight against it.

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    • LibertyLizard@slrpnk.net ⁨4⁩ ⁨months⁩ ago

      Seems like something other states should get in on. Now that the program is established seems like it would not be as hard to pay into it and get a share of the product.

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      • wurstgulasch3000@feddit.org ⁨4⁩ ⁨months⁩ ago

        But that’s socialism! /s

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  • greedytacothief@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

    If I’m remembering the original sysntesis for insulin used dogs, and it was harvest from them after being killed. It’s unjust that insulin is so expensive, but also modern production methods are not the problem here. It’s greed.

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  • TropicalDingdong@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Image

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  • cassandrafatigue@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

    When you kill the wealthy and their enforcers, you should be shouting “blood for blood”.

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    • ameancow@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Since we’re roleplaying you should also say “skulls for the skull throne.”

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      • cassandrafatigue@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

        No. They kill us. They murder people. Make it clear why this is happening, why any negotiation starts with every billionaire shot in the gut and left to bleed out, as a compromise.

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  • JoShmoe@ani.social ⁨4⁩ ⁨months⁩ ago

    I summon, Luigi!

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    • SpaceNoodle@lemmy.world ⁨4⁩ ⁨months⁩ ago

      My name’s not Luigi

      What are you summoning

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      • JoShmoe@ani.social ⁨4⁩ ⁨months⁩ ago

        grunts Damn thing isn’t working.

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  • BootLoop@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

    Canadians: invented drug and patent it freely Americans: Finds way to kill the most people possible while making the most amount of money

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    • Phil_in_here@lemmy.ca ⁨4⁩ ⁨months⁩ ago

      To be fair, the killing isn’t the point; they’re the product. Its just that profit is God, so killing in its name is justified.

      Killing poors for the joy of it? That’s just an evil bonus.

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      • jaybone@lemmy.zip ⁨4⁩ ⁨months⁩ ago

        Killing me soupy with his words.

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  • Wild_Mastic@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Meanwhile, 10 euros per vial here in Europe. At least his original plan for widespread and easy availability has partially succeeded.

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    • djdarren@piefed.social ⁨4⁩ ⁨months⁩ ago

      Free on the NHS in the UK. In fact, diabetes is one of the conditions that qualifies people for free prescriptions across the board.

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    • MissJinx@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Even worst, my dog got it for free from the public vet university for years. They even gave us the syringes. It’s the same human insulin and my dog got it for free. Guess his plan worked better than he thought… only no in the us

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    • jaggedrobotpubes@lemmy.world ⁨4⁩ ⁨months⁩ ago

      It did succeed, humanity just didn’t take the win and run to keep it going.

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    • ChilledPeppers@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

      In brazil 36 reais (about 6 euro). The US is a joke. (And im 99% sure you can also get it for free if you use the public health network)

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      • mika_mika@lemmy.world ⁨4⁩ ⁨months⁩ ago

        I have mental health disabilities in the USA and my meds are at zero cost because I literally have had absolute zero income for the past 5 years.

        You wouldn’t believe how much those mood stabilizer/antidepressant cocktails stack up proportionally when I was able to scrape by on $15 an hour.

        The system set me up to fail with how shitty it is, if healthcare wasn’t crap I could be contributing to society without crippling myself.

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    • neukenindekeuken@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

      In civilized countries at least.

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  • lugal@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

    I really don’t get it. If it was in the freezer, why will it be damaged when put back again? Is it that once defreezed some reaction goes on and shouldn’t be stopped? I really don’t get it. Would it be better to keep it outside the freezer once it warm up?

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    • fullsquare@awful.systems ⁨4⁩ ⁨months⁩ ago

      it might just be in glass vial and freezing broke it

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    • lib1@hexbear.net ⁨4⁩ ⁨months⁩ ago

      Endogenous human insulin is stable up to five freeze-thaw cycles. However, various types of synthetic insulin become less potent once they’ve been frozen. It functionally becomes impossible to know how much insulin you need to compensate for the food you’re eating

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    • Diddlydee@feddit.uk ⁨4⁩ ⁨months⁩ ago

      It was in the fridge, then put in the freezer.

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    • Album@lemmy.ca ⁨4⁩ ⁨months⁩ ago

      It degrades from the freezing process and then dosage becomes unpredictable and thus dangerous. If you have insulin it’s got big words on it saying don’t.

      Heres the side of some humalog:

      DO NOT FREEZE. Store refrigerated at 36°F to 46°F [2°C to 8°C] until time of use. Store in-use vials refrigerated at 36°F to 46°F [2° C to 8°C]. If refrigeration is not possible, store at room temperature (up to 86°F [30°C]). Protect from direct heat and light.

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      • TeamAssimilation@infosec.pub ⁨4⁩ ⁨months⁩ ago

        I’m sure an experienced medic in an emergency could work with it somehow, but for the rest of us living in civilization, insulin that has been outside their recommended temperature range is very dangerous.

        Long-acting insulin has crystals that dissolve at body temperature over time, hence it can gradually release insulin over hours. If you break or dissolve those crystals by freezing/thawing/overwarming, the best scenario would be that it became fast-acting insulin, and it would crash your glucose instantly on injection of your usual dose. The worst scenario is that it no longer acts like insulin.

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    • Brunbrun6766@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Freezing temps breaks down insulin and causes it to lose efficacy which less efficacy is something you don’t want with something that keeps you alive

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    • Daze@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

      Methinks you read it wrong friend; it was stored in the fridge originally

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    • dohpaz42@lemmy.world ⁨4⁩ ⁨months⁩ ago

      It apparently loses effectiveness when subjected to extreme temps, but that loss depends on length of exposure. [Source]

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    • tlekiteki@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

      rea bra

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  • ininewcrow@lemmy.ca ⁨4⁩ ⁨months⁩ ago

    Americans suffer from Stockholm syndrome

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    • ameancow@lemmy.world ⁨4⁩ ⁨months⁩ ago

      I would literally move if I could afford it and if it was even a little easier.

      Stockholm syndrome suggests we enjoy it or want to be here.

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    • PM_ME_VINTAGE_30S@lemmy.sdf.org ⁨4⁩ ⁨months⁩ ago

      Reminder that the term Stockholm Syndrome was coined to blame victims for being rightly more afraid of the police than their captors:

      In [Jess Hill’s] 2019 treatise on domestic violence See What You Made Me Do, Australian journalist Jess Hill described the syndrome as a “dubious pathology with no diagnostic criteria”, and stated that it is “riddled with misogyny and founded on a lie”; she also noted that a 2008 literature review revealed “most diagnoses [of Stockholm syndrome] are made by the media, not by psychologists or psychiatrists.” In particular, Hill’s analysis revealed that Stockholm authorities, responded to the robbery in a way that put the hostages at greater risk from the police than from their captors (hostage Kristin Enmark, who during the siege was granted a telephone call with Swedish Prime Minister Olof Palme, reported that Palme told her that the government would not negotiate with criminals); as well, she observed that Bejerot’s diagnosis of Enmark was made without ever having spoken to her.

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      • fossilesque@mander.xyz ⁨4⁩ ⁨months⁩ ago

        Mod note: Do not make personal attacks towards this user, lest I have to slap more knuckles with a ruler. You can engage with the critique respectfully, or it’s 📏📏📏.

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      • mirshafie@europe.pub ⁨4⁩ ⁨months⁩ ago

        Nils Bejerot was a total hack. He tried to ban comic books, and later transcribed that same energy in a war on drugs that has resulted in some of the worst health outcomes for drug users in Europe. Unfortunately his ability to be confidently incorrect swayed a lot of gullible rubes, and his legacy still casts a shadow over Sweden to this day.

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      • ozymandias@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

        AmeriKKKans

        whoa! so edgy, poignant, and relevant!
        and so creative!
        amazing!
        and everyone clapped

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      • QuinnyCoded@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

        Stockholm syndrome is a proposed condition to explain why hostages occasionally develop a psychological bond with their captors. It is named after an attempted bank robbery in 1973, in Stockholm, Sweden

        ?

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  • TheLeadenSea@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

    I wondered if all the sane Americans did a max exodus to Canada, Europe, UK, Australia etc, what effect that wound have

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    • WALLACE@feddit.uk ⁨4⁩ ⁨months⁩ ago

      Please no, there’s already people rioting over Afghans immigrating here, we don’t need to add Yanks to the equation

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    • Tollana1234567@lemmy.today ⁨4⁩ ⁨months⁩ ago

      the one that have money to migrate to another country have done it already. buts mostly PHD level professionals, rather difficult for people who only have a ms or bs with no established career already. unless you well off enough to be able to move.

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    • turdcollector69@lemmy.world ⁨4⁩ ⁨months⁩ ago

      It’s already happening, there’s been a deluge of affluent people leaving the US.

      We’re still at the stage where it takes considerable privilege to just leave everything behind and pay the exit extortion (40% of all your shit).

      Once things get worse and people have nothing to leave behind you’ll start seeing the engineers/doctors escaping.

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    • pennomi@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Have you looked into what it takes to get a permanent visa to one of those countries? It’s not easy.

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      • Fizz@lemmy.nz ⁨4⁩ ⁨months⁩ ago

        Its not that hard especially for an American.

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      • Master@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

        Its prohibitively impossible.

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    • fossilesque@mander.xyz ⁨4⁩ ⁨months⁩ ago

      I did it a while ago, would recommend.

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      • PM_ME_VINTAGE_30S@lemmy.sdf.org ⁨4⁩ ⁨months⁩ ago

        If you don’t mind sharing, did you have to pay the exit tax? Actually, what was your way out?

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      • Redkid1324@lemmy.world ⁨4⁩ ⁨months⁩ ago

        Aren’t you still paying taxes to the USA? Just curious.

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    • PunnyName@lemmy.world ⁨4⁩ ⁨months⁩ ago

      A lot of us would need financial sponsorship. So there’d be a literal financial drain on those economies.

      I still would like to sign up.

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      • Soup@lemmy.world ⁨4⁩ ⁨months⁩ ago

        Not if you stayed, then it’s an investment. Money doesn’t just disappear when goes to poor people, they use it to buy things like food and stuff. It would only be a financial drain if you were sending that money back home.

        The North American mind cannot comprehend the benefits of supporting the poor.

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