I’m currently writing a small literature review on tgf-b and SMAD signalling in cancer for uni rn
And I’m really confused why this one paper’s talking about how miR-520h induces the tgf-b/smad7 pathway but also binds to and suppresses smad7
Like why on earth is it activating the tgf-b/smad7 pathway, a pathway that stops stuff like the epithelial mesenchynal transition, if it’s just going to bind to smad7 anyway???
Worst thing is, I can’t find any other papers on why this actually happens
I swear I’m just dumb at times ;-;
iAvicenna@lemmy.world 1 year ago
some papers are almost like they are trying to keep the core idea a secret
InputZero@lemmy.world 1 year ago
Unfortunately there’s a bit of pressure to osbficate the core idea of a publication in academia. While the ideal academics try to hold themselves to is to freely exchange information, for researchers who are paid to study very neiche topics there’s an insensitive to put some resistance into others entering their field. There is only so much funding and one more team means more competition. So some researchers who find themselves in that position will intentionally complicate their published work as a way to create a disincentive to others from crowding their field. It sucks but the reality is that funding and money come before the faithful pursuit of knowledge.
Madison420@lemmy.world 1 year ago
Incentive*