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Breakthrough gel can regenerate tooth enamel within weeks

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Submitted ⁨⁨4⁩ ⁨months⁩ ago⁩ by ⁨Domino@quokk.au⁩ to ⁨technology@lemmy.world⁩

https://newatlas.com/medical/protein-gel-rebuilds-tooth-enamel/

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  • HugeNerd@lemmy.ca ⁨4⁩ ⁨months⁩ ago

    Our medical knowledge is shockingly rudimentary. Why we can’t coax cells to do what they did anyway before is something we really need to understand to pretend to have any kind of medical knowledge. What passes for medicine is nothing more than 19th century++. See this, do that, body will heal. That’s about it. I’m shocked every time I see someone in a wheelchair, how can we have LLMs and hallucinated movies but not understand how a few milligrams of organic matter organizes into nerves? etc etc etc

    I am hoping that the absolutely bonkers computing power we are currently wasting on fart videos will be used to simulate matter in the future, here’s to cheering on the AI crash!

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    • Jumpropegazing@lemmy.zip ⁨4⁩ ⁨months⁩ ago

      we do have the ability to coax cells and even turn differenciated cells into pluripotent stem cells we’ve been able to for years the people who did it won a nobel peace prize

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    • MumboJumbo@lemmy.world ⁨4⁩ ⁨months⁩ ago

      In reality, AI will help solve a lot of our medical ignorance. Not the goofball LLMs, but specialized AI algorithms specifically geared towards niche medical research and applications. Don’t let GPT and Gemini sour the potential of some possibly game changing software.

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    • frongt@lemmy.zip ⁨4⁩ ⁨months⁩ ago

      The human body is an immensely complex system of chemical reactions.

      And before you say “simulate it”, we don’t have nearly enough computational resources to do that. Simple reactions or chains of reactions, yes, but even a simple body process consists of multiple steps and a number of large, complex molecules.

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      • Doomsider@lemmy.world ⁨4⁩ ⁨months⁩ ago

        This right here. We can definitely model how a single chemical effects cells, but what about multiple chemicals. The reality is we are still very far from simulating something like the side effects from multiple interacting drugs at once.

        We will likely discover some incredible insights when we do this though.

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    • Soggy@lemmy.world ⁨4⁩ ⁨months⁩ ago

      We have a pretty good idea how things work during development, it’s tricking those cells into the same process as a fully-formed organism that’s hard. Isolating and distributing the hormones in the right way. I think you’re underselling the complexity and scale of biology. We can’t just put a tiny camera and chemo-sensor inside a neuron and see what’s going on in real time and synthesize up a hundred thousand copies.

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      • HugeNerd@lemmy.ca ⁨4⁩ ⁨months⁩ ago

        That’s my point, we’ll simulate it.

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  • wabafee@lemmy.world ⁨4⁩ ⁨months⁩ ago

    I bet the catch here is it could accidentally grow anywhere in the body as long as it mimics what our mouth has (saliva). Imagine growing enamel in our tongues or throat.

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    • AwesomeLowlander@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

      Doesn’t matter without an anchor point

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  • FrostyTheDoo@lemmy.world ⁨4⁩ ⁨months⁩ ago

    I no longer get excited about medical innovation because I know I’ll never be able to afford to benefit from any of it. I’m lucky to have gotten vaccinated as a child while that was still legal for the poors

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    • cmbabul@lemmy.world ⁨4⁩ ⁨months⁩ ago

      If this is legit and dental industry doesn’t try to drown it in a bathtub I’ll be fucking shocked.

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      • partofthevoice@lemmy.zip ⁨4⁩ ⁨months⁩ ago
        [deleted]
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    • jerkface@lemmy.ca ⁨4⁩ ⁨months⁩ ago

      When I was a teenager it was announced that we would soon be able to stimulate the growth of brand new teeth, right in the mouth. I’m almost 50 and I need some new fuckin’ teeth real soon.

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      • Jumpropegazing@lemmy.zip ⁨4⁩ ⁨months⁩ ago

        its possible now but the world is pretty fucked. we can already reduce aging too and reverse it, we have cancer treatments that have near 100 percent success rates for many cancers, and many of these developments were only in recent years but when you watch how much gets done without making it into actual hospitals because of shitass companies and practices it makes you feel a little concerned if any of that will really have an impact, especially when everything is already burning anyway…

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      • HugeNerd@lemmy.ca ⁨4⁩ ⁨months⁩ ago

        No offense, but unless you have some sort of condition like not growing enamel, what have you been doing for your teeth to be that bad at not even 50? Chewing on anvils and flossing with barbed wire?

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      • kiagam@lemmy.world ⁨4⁩ ⁨months⁩ ago

        There was a new development in japan less than a year ago. Downside is all your teeth fall out and all regrow

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      • SaveTheTuaHawk@lemmy.ca ⁨4⁩ ⁨months⁩ ago

        The problem is those new teeth were soft with no enamel. This could address that. Either way, no insurance will cover this and it will cost a fortune.

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  • FuCensorship@lemmy.today ⁨4⁩ ⁨months⁩ ago

    How many times have I read this headline…

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    • REDACTED@infosec.pub ⁨4⁩ ⁨months⁩ ago

      My only question is - when will it be available?

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    • tempest@lemmy.ca ⁨4⁩ ⁨months⁩ ago

      Every time you read it it’s in a mouse or a petri dish.

      I wish they would put that on the headline.

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      • stoly@lemmy.world ⁨4⁩ ⁨months⁩ ago

        There’s a big difference between doing something in a lab and mass producing it for millions of people.

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      • Lightfire228@pawb.social ⁨4⁩ ⁨months⁩ ago

        According to the article, they used human teeth from cadavers

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  • Tollana1234567@lemmy.today ⁨4⁩ ⁨months⁩ ago

    isnt that why naHp DOES already in a dental setting, but there hasnt been definitive studies where its conclusive with OTC usage, eventhough there are tons of nahp products out there already from 5-10% with extremely questionable concentration and efficacy.

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  • pastermil@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

    Hopefully in the right place.

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    • ChaoticEntropy@feddit.uk ⁨4⁩ ⁨months⁩ ago

      Behold my new chitinous armour plates!

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      • Soggy@lemmy.world ⁨4⁩ ⁨months⁩ ago

        Don’t give the military ideas like that.

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    • FatVegan@leminal.space ⁨4⁩ ⁨months⁩ ago

      Congrats, you’re now a narwhal

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      • Snowpix@lemmy.ca ⁨4⁩ ⁨months⁩ ago

        Narwhals, narwhals, swimming in the ocean

        Causing a commotion 'cause they are so awesome

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  • fubarx@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Side effects: sharp fangs and uncontrollable drooling.

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    • awful_neutral@lemmy.blahaj.zone ⁨4⁩ ⁨months⁩ ago

      Win win

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  • ZILtoid1991@lemmy.world ⁨4⁩ ⁨months⁩ ago

    How long until the dental restoration industry lobbies it out to be banned, so they can keep selling their photoshop jobs of people smiling with new teeth alongside crowns and implants, all at an inflated price?

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    • Wispy2891@lemmy.world ⁨4⁩ ⁨months⁩ ago

      It already happens with nano-hydroxyapatite pastes. In Europe you find them at the supermarket for 5 euro, in USA you need a prescription and it’s sold for $$$

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      • axum@lemmy.blahaj.zone ⁨4⁩ ⁨months⁩ ago

        Uh no. You can get nHA toothpaste in the USA without a prescription, not sure why you’d think that. It’s just not a popular item here so it’s not sold at brick and mortar stores for the most part, though some smaller stores have it. But I have no problem ordering the stuff online.

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  • Victoriathecompact@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

    gimmie

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  • MIDItheKID@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Hell yeah. I’m gonna overuse this shit and just have 2 gigantic teeth. One on the top and one on the bottom. No more flossing for me. Fuse those bad boys together. I’ll have the smile of an N64 game character.

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    • frongt@lemmy.zip ⁨4⁩ ⁨months⁩ ago

      I think that’s just called dentures

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    • Soggy@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Settle down Mitch Hedberg.

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    • SabinStargem@lemmy.today ⁨4⁩ ⁨months⁩ ago

      Image

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      • DoucheBagMcSwag@lemmy.dbzer0.com ⁨4⁩ ⁨months⁩ ago

        What could PAWSIBLY go wrong?

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    • Chill_Dan@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Gotta get that cartoon chin as well.

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      • HeyThisIsntTheYMCA@lemmy.world ⁨4⁩ ⁨months⁩ ago

        if you’re gonna get chin work, make sure you have a butt chin (with a smaller, extendable butt implant installed in the cleft)

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    • CordialCephalopod@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Currently sitting in an Uber relying on autocorrect to spell for me. I don’t want to belly laugh and make my driver think I’m a crazy person fuk u

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  • Sam_Bass@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Not gonna help anyone with broken ones

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    • IlmariGanander@lemmy.wtf ⁨4⁩ ⁨months⁩ ago

      There’s another treatment on the horizon though that grows entirely new teeth. There’s an article with a pic of a ferret showing an entirely new tooth that was grown. I think it’s a research group in Japan that managed it?

      These techs together mean some pretty exciting things coming in a decade or two for shitty teeth when the technologies mature.

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    • moncharleskey@lemmy.zip ⁨4⁩ ⁨months⁩ ago

      You’re fun at parties, huh?

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  • Simulation6@sopuli.xyz ⁨4⁩ ⁨months⁩ ago

    Can they make one to generate beaver enamel? I will accept the red color if I can chew through a tree.

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    • Tollana1234567@lemmy.today ⁨4⁩ ⁨months⁩ ago

      beaver have a different composition, its made of iron compounds, i dont think human mouths are adapted to have iron teeth, it might damage your other teeth, because iron is much harder than calcium hydroxyapatite.

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    • HeyThisIsntTheYMCA@lemmy.world ⁨4⁩ ⁨months⁩ ago

      there are times i think about getting titanium caps, but my one crown does not feel great and i don’t like how mouthpieces feel

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  • samus12345@sh.itjust.works ⁨4⁩ ⁨months⁩ ago

    Image

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  • DaddleDew@lemmy.world ⁨4⁩ ⁨months⁩ ago

    You’re telling me I’ve been brushing twice a day all my life for nothing?

    Man, what a bummer.

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  • MonkderVierte@lemmy.zip ⁨4⁩ ⁨months⁩ ago

    Without burning your tongue this time?

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    • some_kind_of_guy@lemmy.world ⁨4⁩ ⁨months⁩ ago

      First you must remove the tongue

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  • kokesh@lemmy.world ⁨4⁩ ⁨months⁩ ago

    I’ve heard about something like this back in 90s for the first time. I guess we won’t see anything ever. Big tooth won’t allow it 😂

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  • AmidFuror@fedia.io ⁨4⁩ ⁨months⁩ ago

    The researchers used extracted human molars as an ex vivo model, first etching their enamel or dentine surfaces with acid to mimic different stages of tooth erosion. They then applied a single coating of the biomimetic elastin-like recombinamer (ELR) gel and let it dry. Finally, the teeth were immersed in carefully controlled mineralization baths that replicated the ionic environment of saliva.

    Keep in mind this hasn't been shown to actually help teeth in someone's mouth.

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    • Gigasser@lemmy.world ⁨4⁩ ⁨months⁩ ago

      My guess is that they can slowly regrow lost enamel under fillings, slowly build back up later by layer until a filling is no longer needed. What would be amazing is a cure for gum disease.

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    • Goretantath@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Just from that, it seems like its a patch job, not capable of regrowing from zero.

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      • mastertigurius@lemmy.world ⁨4⁩ ⁨months⁩ ago

        To be fair, the research is on regenerating, not regrowing. I wouldn’t expect regrowing lost teeth to be possible any time soon, unless some kind of bio 3D-printing method became available.

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      • umbrella@lemmy.ml ⁨4⁩ ⁨months⁩ ago
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  • Endymion_Mallorn@kbin.melroy.org ⁨4⁩ ⁨months⁩ ago

    When I can access it, I'll be happy.

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  • Sibbo@sopuli.xyz ⁨4⁩ ⁨months⁩ ago

    I’m not sure if this is a good thing. Just imagine how many people will just stop brushing their teeth and smell worse than trash cans when you talk to them.

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    • dharmacurious@slrpnk.net ⁨4⁩ ⁨months⁩ ago

      “We shouldn’t be setting bones and giving people casts. Just imagine how much more reckless people will be if they don’t have the threat of deformity and lifelong pain!”

      Let people have nice teeth, even if maybe they didn’t take the greatest care or them as young folks, or grew up eating highly acidic foods or drinking soda.

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    • Nurse_Robot@lemmy.world ⁨4⁩ ⁨months⁩ ago

      Probably no more than already?

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  • MeekerThanBeaker@lemmy.world ⁨4⁩ ⁨months⁩ ago

    I’ve heard of stuff like this for well over a decade. Seems like there’s a new article about teeth regrowth every month, either enamel or full teeth. Still waiting on real results.

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    • Rooster326@programming.dev ⁨4⁩ ⁨months⁩ ago

      I fully believe most dentists would rather kill the inventor of whoever lets us regrow teeth for cheap than let it come to the light of day

      Change my mind.

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      • snooggums@piefed.world ⁨4⁩ ⁨months⁩ ago

        Dentists make a lot more money off of major repairs and general maintenance than they do by replacing teeth entirely.

        Oral surgeons on the other hand do make money off major repairs to damaged teeth or teeth replacements. I know people often call anyone who works on teeth a dentist, but technically they are different professions.

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      • DarrinBrunner@lemmy.world ⁨4⁩ ⁨months⁩ ago

        The only way this sees the market is if it is nerfed to require reapplication every six months.

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    • Valmond@lemmy.world ⁨4⁩ ⁨months⁩ ago

      It’s the new new battery tech!

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      • CheeseNoodle@lemmy.world ⁨4⁩ ⁨months⁩ ago

        But batteries consistently improve year on year, we just keep increasing the demand of our devices in lockstep because 10% more powerful! markets much better than 10% more battery life.

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      • FordBeeblebrox@lemmy.world ⁨4⁩ ⁨months⁩ ago

        Battery tech is the new fusion, just 10 years away!

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      • snooggums@piefed.world ⁨4⁩ ⁨months⁩ ago

        We have had massive improvements in batteries so that bodes well!

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    • NauticalNoodle@lemmy.ml ⁨4⁩ ⁨months⁩ ago

      It’s a subject that targets people’s deep-seated insecurities. Everybody wants a tooth that can regenerate when they first discover a cavity for themselves.

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      • corsicanguppy@lemmy.ca ⁨4⁩ ⁨months⁩ ago

        With enamel regrowing constantly after the smallest scratch, cavities cannot get to where they form.

        This hokum story is promising no more cavities ever.

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    • turdas@suppo.fi ⁨4⁩ ⁨months⁩ ago

      The teeth regrowth thing was only two years ago.

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      • SnotFlickerman@lemmy.blahaj.zone ⁨4⁩ ⁨months⁩ ago

        www.frontiersin.org/journals/physiology/…/full

        It’s been in the works for over ten years. Here is a paper from 2014.

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  • mastertigurius@lemmy.world ⁨4⁩ ⁨months⁩ ago

    “Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life against physical, chemical, and thermal insults,” said lead author Dr. Abshar Hasan

    This man doesn’t just disapprove of people mistreating their teeth, he is personally insulted by it. A true dentist.

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  • crank0271@lemmy.world ⁨4⁩ ⁨months⁩ ago

    Finally, my dream of making teeth anywhere you can imagine could be realized.

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  • otacon239@lemmy.world ⁨4⁩ ⁨months⁩ ago

    It would be really incredible if they can manage to make this an OTC offering. This is huge.

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