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First-In-Human Trial Of CRISPR Gene-Editing Therapy Safely Lowered Cholesterol, Triglycerides

⁨55⁩ ⁨likes⁩

Submitted ⁨⁨3⁩ ⁨days⁩ ago⁩ by ⁨AfterNova@lemmy.world [bot]⁩ to ⁨technology@lemmy.world⁩

https://finance.yahoo.com/news/first-human-trial-crispr-gene-145600945.html

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Comments

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  • Nioxic@lemmy.dbzer0.com ⁨3⁩ ⁨days⁩ ago

    Why would you lower cholesterol?

    The body literally makes it because you need it. People with high cholesterol live longer…

    pmc.ncbi.nlm.nih.gov/articles/PMC11901585/

    Youd wanna lower arterial plaque so cholesterol doesnt get stuck?

    An arterial calcium scan is the best indicator for heart disease etc.

    Not cholesterol.

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    • TranscendentalEmpire@lemmy.today ⁨3⁩ ⁨days⁩ ago

      The body literally makes it because you need it

      For what?

      People with high cholesterol live longer…

      I don’t think that’s really a conclusive study. It only focuses on people who are already 80 or older and ignores the majority of people who suffer from cardiovascular issues that don’t make it to their eighties because of it.

      From this study you could also conclude that people who have a natural resistance to high cholesterol live longer.

      Youd wanna lower arterial plaque so cholesterol doesnt get stuck?

      Plaque forms when cholesterol lodges to the walls of arteries. This happens at a greater rate when you have more lower density cholesterol in your blood.

      An arterial calcium scan is the best indicator for heart disease etc. Not cholesterol

      But calcium buildups are formed from clacified plaque, which is made from cholesterol…

      If all forms of high cholesterol were really beneficial Americans would modern day Methuselahs.

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    • mholiv@lemmy.world ⁨3⁩ ⁨days⁩ ago

      You need to reach out to the scientists to let them know! You could save lives with your insight!

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    • Beacon@fedia.io ⁨3⁩ ⁨days⁩ ago

      No dude, you're WAAAAAAY overstating what that paper says.

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  • Beacon@fedia.io ⁨3⁩ ⁨days⁩ ago

    Bring it on!!!

    Autoimmune disease? GONE!

    Acne? GONE!

    Don't like your eye color? CHANGE IT!

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    • FerretyFever0@fedia.io ⁨3⁩ ⁨days⁩ ago

      Shit's going to get pretty weird imo. Hopefully it isn't used for eugenics purposes (it probably will be, let's be honest). I don't think that people should be able to change so many things that they become unrecognizable, but I can understand changing a few things per person, voluntarily, obviously.

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      • black_flag@lemmy.dbzer0.com ⁨3⁩ ⁨days⁩ ago

        There are a lot more problems in trying to create the infrastructure to enforce sanctioned uses of any readily accessible technology than there is in the use of said tool. The people who want to do the most harm inevitability wind up in the oversight position, while society tends to create enforcement mechanisms at a social, interpersonal level organically already.

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      • Beacon@fedia.io ⁨3⁩ ⁨days⁩ ago

        I believe in bodily autonomy. People should be able to do whatever they want to their own body.

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