Comment on The holy journey
daannii@lemmy.world 1 day agoLsd is often distributed and consumed via small paper squares called blotter paper. The paper is thick like cardstock. Sometimes with colorful psychedelic artwork printed on it.
The lsd is diluted in a solution and the paper is soaked in the solution. Usually alcohol.
The tiny microscopic lsd crystals deposit on the paper. The blotter paper is divided into 1cm squares.
Lsd is neutralized by many chemicals , including chlorine (found in tap water) and stomach enzymes. It cannot be swallowed and still have an effect.
To take LSD, a person will place squares (typically one square is 1x 100ug dose) of the paper on the tounge or under it. And hold for about 15 minutes. Some people take more than one. It can’t kill you. But it can lead to accidents in high doses that can kill you. So it’s not risk free even if health risks are low.
Also I said ug. Not mg. The lsd drug is very unique in that it has high potency at micrograms. Fentanyl is another drug that has that property . But it is rare.
The lining of the mouth (mucus membranes) allows for easy transfer of the drug into the blood stream. That’s true for a lot of drugs actually.
This is why lsd has such a unique drug delivery method though. It can’t be swallowed and it should be used in very small doses.
Lsd is also very resistant to degeneration. Oxygen, sunlight, and neutralizing chemicals like chlorine can degrade it. But if it’s stored properly it can last a very very long time. This is another rare property it has.
It’s also clear, tasteless, and no odor.
I’m a perception researcher and , of course, this would be a drug on my radar. So I know quite a bit about it. I’ve given a lecture on psychedelics. It’s a fascinating topic.
Also I’m generally interested in psycho-pharmacology because , well, it’s interesting.
If you want to learn more interesting facts about LSD and other psychedelics, ask away.
Incorrect about acid in the stomach. Most DOX and nbome chems are neutralized by stomach acid and during the mid 2010 acid drought swallowing tabs was considered the simplest way to avoid unwanted DOX trips.
Source: the hundreds of tabs that I swallowed and still had a good time
I took DOC back in the 00s (on purpose) and it was an extremely wild 20-some hours. Second weirdest thing I’ve done (the weirdest is Foxy by a WIDE margin,) but I still had a relatively good time due to having a great and comfortable set and setting. By hour ten, I was VERY ready to be done.
I was too poor to care, been on plenty of non acid trips on chems that lasted wayyy too long. Some were really fun, some were abject terror. Never got to try foxy sadly. MXE was the strangest chem I’ve tried and holey hell, I turned into an interdimentional worm crawling through the multiverse. It was super overwhelming.
I never tried MXE! I wanted to as I have enjoyed ket in the past, but the times I was offered MXE, I just eas not in the right headspace/environment.
Foxy is fucking insane. It had the normal visual and auditory hallucinations, but it’s the only thing I’ve ever tried that gave me full on temporal distortions. My partner-at-the-time and I were listening to familiar music. The music would get lower in pitch and streeeetch out, each individual note playing for longer and longer, until the tone went back to normal and the notes stopped being played for so long. When it was low and slow, our bodies got soooo heavy, we would just lay on the floor. When the notes got fast and higher pitched, our bodies would be light with energy. VERY weird stuff.
Most drugs/medicines are taken in higher doses because the body filters or neutralizes the compounds so much that only a small portion gets into the blood.
That’s still different.
Even if the total quantity of the drug is small in the system once it gets there, it’s not the same as how LSD works. The drug, likely because of its similarity to serotonin and size , is readily absorbed into the blood stream and passes the blood brain barrier easily. It is not filtered out to a small percentage of it’s original dose like most drugs/medicines.
You surely are aware of this ?
There are very few drugs that can work in small dosages like LSD. As I said, fentanyl is one.
I’m not sure what you are talking about with dox trips.
Drugs like DMT /Ayahuasca also can’t be ingested unless they are mixed with a maoi inhibitor.
Most psychedelic research chemicals (nbome) are much different than lsd with different pharm and effect properties.
It’s possible that LSD is released more quickly on the tongue than nbome drugs. So as soon as it hits the tounge the drug is delivered. I don’t think there is research on this. But I’ll look into it.
But this idea that it’s not neutralized in the stomach is false. There is plenty of research on that.
Look up Clonazepam, I’m not going to argue with somebody that is as confidently incorrect as you are. I have a decade and a half of subjective experience and personal research into the chemicals I have put into my body, and spent countless hours talking with people that know even more than I do. Yes, LSD is very active in small amounts. So are plenty of other chemicals and calling it unique because of that is incorrect.
Also, stomach acid does nothing to neutralize LSD in any meaningful way, please stop saying that.
Yeah this bozo has no clue what they’re talking about.
So take lsd and go star gazing.
Yes, but… it’s really hard to stay focused. Everything is kinda awesome to look at, so I have forgotten about the stars and zoned on my surroundings or my hand or a hundred other things. I like tripping in the woods or at the beach best personally.
Novelty is a common effect that people don’t talk about much. Essentially it makes everything seem new and novel.
What’s interesting is, in the brain there is a specific spike in electrical activity (called event related potential, or ERP) that happens when you look at something new and unexpected. Some call it the novelty indicator. Designated P3a.
You can measure it with eeg equipment (electrodes on the scalp).
I’d be really interested to see if that ERP is happening more on LSD. It might shed more light on the mechanisms of the drug. If it doesn’t happen, then it would challenge the theory of what the P3a is.
I personally think LSD has a lot of potential to be used to research perception processing in the brain.
Too bad it’s basically impossible to get approval to use it for that reason.
hell yeah
I believe the phrase is taking an lsd
They’re divided in 0.5x0.5 cm.
You can totally eat a tab and still get high.
Nowadays is hard to find 100ug doses. The minimum I had found is 150ug. Anything over 400ug isn’t LSD but Nbomb that is dangerous and should be avoided.
Ugh I do not miss 25i. Put a blotter on my tongue, taste it IMMEDIATELY, spit that shit out.
(This might have been mentioned and crooner definitely already knows this, but to others interested: LSD has zero taste at all. It just tastes like the paper it’s on (or gummy, faint grain alcohol if you’ve got a vial, etc)
I gave up on LSD because it lasted way too long and finished not enjoying it, until talking with a friend I commented that the I also hated the sour flavor of it and he was like dude that was nbomb not LSD. The he gave me some actual LSD and it was way more pleasure experience, not as high, but the experience didn’t extend as long and the landing was confortable.
Bitters a spitter, gimme my money back
Ah yes you are correct. I definitely mis reported the size. It’s 5x5mm
Honestly, damn. That sounds like a very interesting topic. If I wanted to learn more what resources would you recommend? (preferably textbooks/articles)
This person is an unreliable source fr information on LSD.
You know there isn’t much in a single location aside from Wikipedia.
In textbooks I’ve come across , there is discussion of the pharmacology properties or a brief note about counter culture and general effects.
There is limited research on the drug as it’s been black listed for almost 50 years and even now, it’s primarily only researched for terminally ill people/mental health. Only a handful of those studies exist and none use double blind controls so the science quality is poor.
I myself am not convinced it has mental health benefits due to the way the drug works. It does however have strong suggestive effects meaning the drug itself promotes placebo/expectation effects.
The lecture I put together for my class (perception and sensation ) pulled info from a wide range of resources.
However there is one organization trying it’s best to do modern research and they have done some MRI studies. There was also a study on LSD and synesthesia which sheds a lot of light into the mechanisms. MAPS is the organization. maps.org
They have videos on YouTube with researchers discussing the research and studies they have done. But they mostly focus (last few years at least) on it’s use in mental health.
The drug property information I know about is mostly pulled from old research from the 60s before the research bans. A lot was done on animals to understand dosage and half life. The cascade effects of how this drug works are still not really understood. We do know that the drug is similar in structure to serotonin. But there are still a lot of unknowns.
Let me dig around for my resource links. I have a few interesting studies I found when preparing the lecture, including the synesthesia one, and I’ll organize it all and I’ll put a link up to a g drive with it.
The lecture I did was 3 hrs long about hallucinations with a chunk dedicated to psychedelics. It did rely on other lecture materials to understand or otherwise id just put it up. (It was the final lecture for the class so it referred back multiple times to previous lessons). But maybe I can re-write it a bit. I’ve honestly been thinking of turning it into a video for a while because there are so few resources out there that review it more broadly. And a hell of a lot of misinformation about hallucinations and psychedelics.
Basically this lecture was on hallucinations and the primary causes and how each of these causes relies on the same root changes in brain processing.
For instance. You are driving on a country road at night. Vigilant to look for deer. Multiple times you were sure you saw an animal near the road but soon realized it was a fence post. Or an old glass bottle reflecting your headlamps. But for a split moment you did see an animal there before you corrected the perception.
What ultimately caused that is what causes hallucinations in other situations. Like schizophrenia and drug use.
So we circle around neuroscience, psychiatry, physiology, and pharmacology. As well as cultural impacts influencing the experience of hallucinations or psychedelics.
This is getting long. Apologies. The lecture is 3 hrs and relies on many other hours of information. It’s a big topic.
All this and you don’t even link to erowid?
www.erowid.org/chemicals/lsd/lsd.shtml
You don’t seem like a very good researcher.
also, PsychonautWiki…
Erowid is personal opinions of drug users.
FUCKING EROWID
How much acid have you taken yourself? Because it definitely works when swallowed.
After re checking this information, I believe I was confusing DMT and LSD properties of not being active when ingested.
I remembered DMT can’t be ingested but I was sure it was true for LSD. But I was mistaken. LSD is neutralized by base not acids.
You can definitely swallow it
Your stomach acid will definitely neutralize it. But after having it on your tongue for a while the drug has been deposited into your system.
You’re confidently wrong:
www.sciencedirect.com/…/S2772632023000338
Mate the first line of that publication is flat wrong
This review is on lysergic acid diethylamide (LSD), which has a halogenic effect and is addictive.
LSD is not addictive. I’m not going to bother reading any farther after such a ridiculous claim.
That is incorrect
Wait, is two tabs unusual? Like sure the default among my friends was one, but two is for when you really want to experience it and is more for constructive trips or to hallucinate and three is for when you need even more but you’re playing with fire there
I mean it depends on the person and the dose on the tabs. Like most recreational illegal drugs, it’s hard to know how much is actually present on the tabs.
Many times drugs are diluted at various steps of transport and selling. Though it is harder to do that to a drug already on paper like this.
And where do we get it 😂
Dark web
tomiant@piefed.social 15 hours ago
LSD absolutely can be swallowed, I don’t understand where all these myths come from and how they keep being propagated over decades and decades when it is a very simple thing looking it up.