phdepressed
@phdepressed@sh.itjust.works
- Comment on Important update: It's 10 poptarts 5 days ago:
Why you putting poptarts on pizza?
- Comment on Important update: It's 10 poptarts 5 days ago:
The filling is like a bad taxidermy. You know what it is but it’s just not right. Icing is more of the same. The biscuit(?) part is cake flavored cardboard.
- Comment on Brad buys a house 1 week ago:
Yeah, basically what happened to Florida and a part of why it went from swing state to Red.
- Comment on Brad buys a house 1 week ago:
Yeah, moving to lower cost of living will make you relatively rich. It’s a reason people sometimes retire to rural (lower tax-red) areas. However, If you’re still working the usual problem is that the jobs also pay less and “amenities” are also less. Fewer good restaurants, less option for entertainment, worse schools, etc.
- Comment on Use this science wisely. 2 weeks ago:
Honestly, me and wife on that one. Sure we’ve tried it but neither of us really enjoyed it. So we haven’t done it again…doesn’t stop me from making the jokes though.
- Comment on Do you think he'll respond? 3 weeks ago:
Specifically for medical stuff, they swipe your number and email when you take the MCAT. I was debating an MD/PhD so I took it and even never applying or getting into med school they’d randomly email me, for like 5y after.
- Comment on I'll take care of it Alfred 3 weeks ago:
What a terrible day to have eyes.
- Comment on [deleted] 4 weeks ago:
Neither grandpa knows guns and ironically enough would likely be against actually owning them. I already know how to use a gun since I’m from SC and had friends take me skeet/target shooting. However, I’m currently in NY where ownership is a major pain and personally dont trust a gun in my home.
- Comment on [deleted] 4 weeks ago:
Something along those lines might work. Not so much “adamantly” but yeah they’re often repetitive, just part of who they are. The grandpas at least aren’t meaning to come across as they are, which is why I haven’t gone the direct confrontation route, from other experience that doesn’t go well but well worded “snark” or sarcasm oddly enough seems to work. These are old brown men who have improved a lot over the years. Knowing how to confront them in a way that leads to a desired effect is a skill.
Idk maybe I’m not treating this with appropriate concern, my childhood was filled with older women telling me I’d be a lady killer when I grew up, pinching my cheeks, and asking to steal my eyelashes…
- Comment on Every damn time. 4 weeks ago:
Think like a microchip but for cells. These organ on a chip contain various cells to emulate the function and response of an organ.
I recommend finding a different hobby as salt up your urethra sounds unpleasant. But I mean if your partner is into it whatever.
- Comment on Every damn time. 5 weeks ago:
Yeah, because it’s fast and little pain can be felt before its dead. Guillotines were developed to be a more humane execution for people.
“Physical methods” (Guillotine, cardiac puncture, thoracotomy, etc) are usually a secondary confirmation of death after lethal ketamine/xylazine cocktail injection, isofluorane, or CO2 inhalation.
And yeah we’re sacrificing them to the science god to try and make new discoveries and new therapies. We’re also trying to develop ways to avoid using organisms such as organ on a chip or multiple organ on a chip systems but thats expensive af and not yet sufficient quality to replace organism testing.
- Comment on nothing against that guy, but this was a funny glitch 5 weeks ago:
Lot of reasons behind the replication crisis that basically boil down to two main things. 1) fraud and 2) really miniscule stuff that isn’t practical to consider.
So 1 is pretty self explanatory. 2 for an example can be something as minute as a slight temperature change in what the animal facility is kept at. Or even the time of day animals or cells were treated.
- Comment on Can you house-sit instead of renting? Australians turn to pet-minding to escape the housing crisis 5 weeks ago:
If you’re paying to housesit then it is just an Airbnb with extra rules.
- Comment on OpenAI claims GPT-5 AI model can provide PhD-level expertise. 5 weeks ago:
Don’t need to steal a lot of journals made deals.
- Comment on Would we be able to use the measles virus to reset the immune systems of people with autoimmune disorders like MS or rheumatoid arthritis? 5 weeks ago:
Aside from some comments mentioning how immune reset therapies are in fact a thing through either antibody or chemical depletion of your immune cells. These can show improvement but it is very far from curative and not too much better chances than existing immune suppression stuff.
The danger to an immune “reset” are that you are generally then able to be reinfected with every cold and flu as well. This is dangerous for older or already fragile people. The existing therapies reduce this danger by not entirely wiping memory cells out but that also means they aren’t always curative.
Beyond that autoimmune diseases in general are a mix of genetics and environmental factors (and even gut bacteria by some studies). If the underlying problem isn’t fixed then relapse is a question of when not if. It’s like adding fluid to a container with a leak, eventually you’re going to have to add more again unless you fix the leak first.
So we have to find where the “leaks” are, what they are caused by and fix the cause(s) to have something that is an actual cure. Right now we mostly know where the leaks are and some causes and can patch some up leaks up. However, we don’t have a way to fix the causes yet and we dont know all of them.
*I am a cell bio PhD but not an immunology specialist.
- Comment on Sup, guise. 1 month ago:
No you add DMSO (5-10%) and freeze slowly. Using a Mr frosty or similar. Otherwise a few hours at -20, then -80, before the LN2.
Just chucking in LN2 is going to have terrible recovery. That might have been done with HeLa way back when but certainly isn’t standard anymore.
- Comment on Sup, guise. 1 month ago:
I’ve used an enzyme from West Germany. Worked great.
- Comment on Pattern Recognition 1 month ago:
I mean its like the top category for the last some years in the US as well. Elon’s dad has multiple children with a woman who was his adopted daughter. The pedo in chief is on TV talking about how attractive his own daughter is. Listening to women and stories of sexual abuse by family are a dime a dozen. I unfortunately don’t think it is just a regional thing but that they are more open with it and don’t take the effects of it seriously.
- Comment on [deleted] 1 month ago:
At 22 I didn’t want kids. At 32 I have a kid without regrets. Prior to getting a long-term partner with the same mindset I think it is a bit much unless something or someone has scared you about “baby trapping”.
Vasectomy reversal can usually be done but isn’t always effective.
- Comment on Pattern Recognition 1 month ago:
There’s a disturbing trend of pseudo or outright incest in Japanese media. Step siblings, cousins, actual siblings, etc. I mean western porn does it too with step-whatevers but it at least isn’t in kids cartoons afaik.
- Comment on Be nice 1 month ago:
Less tracking? Marginally lighter physical wallet? Idk, crypto is a scam as far as I can tell. Sure you can make a whole bunch of money and we’ve decided its legal but its somehow both an investment where you can make and lose millions and a currency to pay for absolutely nothing I’ve ever seen. If there was just one or if a few were based around NAFTA, BRICS or EU whatever it could make sense. But every scummy podcaster and 4chan memer makes their own to scam the participants.
- Comment on Be nice 1 month ago:
That could actually make it a viable currency. Unless you mean the entirety of all bitcoin in which case lol.
- Comment on [deleted] 1 month ago:
I can’t speak to it as I haven’t done one but I can get the desire. I never went on a date or had a gf or any sexual experience until I was 25 and it wasn’t for lack of trying…paying for it would be a sort of bandaid to the issue of loneliness but I wonder if it decreases the chance of becoming an incel.
- Comment on [deleted] 1 month ago:
If you think about having a gf, there’s a lot more to the relationship than sex. Nonsexual physical intimacy, much less anything emotional is extremely lacking for the average male not in a relationship.
- Comment on It's not just kind, it's kinder 1 month ago:
Quite possibly, it was rather popular in my middle school and I think MCR or some other popular band did a music video with them.
- Comment on Itch.io apologise for "frustration and confusion" after delisting thousands of NSFW projects 1 month ago:
That’s literally what calling your government representatives is. You’re supposed to be able to pressure your representative to represent you.
- Comment on Is the peoples deep interest in chemical experiment viral videos (e.g. liquid nitrogen in a pool) related to being shooed away from understanding real science? 1 month ago:
A lot of scientists are not great communicators. I am much better over text than I am in person… I never shoo anyone away in person but I also understand that in social settings most people only ask what I do out of courtesy rather than genuine interest.
People enjoy the way certain people share their passion. This is a bit overdone for gaming channels focused on kids e.g. pewdiepie but there’s also the dude building a hut with Neolithic tools, or tasting rations, trying new foods, or just reacting to fried rice (uncle roger), gardening, or powerwashing. Nilered shares his passion for chemistry in a way a lot of people enjoy but for better or worse I don’t think it is about understanding Nature as much as it is connecting with a fellow human.
PhDs are philosophy degrees because whether on purpose or not theses are filled with the personal philosophy of the writer wrapped in the paper of whatever research.
- Comment on How much of a persons body is needed to survive? 1 month ago:
Yeah, as with most implants there are issues with biofilm/plaques and immunity. They are also not responsive to loading so don’t allow exercise, affect vasculature weirdly etc.
- Comment on How much of a persons body is needed to survive? 1 month ago:
Communication only needs the brain nowadays, neuralink is shit but there are options for similar brain-machine interface that are workable for paralyzed people.
Survival is harder. Ecmo, parenteral nutrition, and dialysis are organ supplements not replacements. Lacking lungs, GI, or kidneys will kill you. Dialysis supplements kidney function. Ecmo supplements lungs that are reduced capability. Parenteral nutrition supplements reduced GI function. There are mechanical hearts/assitive devices one dude had a mech heart one for years but you still need blood pumping. The liver has no assitive device you die in 24h without.
- Comment on YSK Doctors of Osteopathy in the US seldom practice Osteopathy 2 months ago:
Yeah, that’s some chiropractic bullshit. With EDS you have a much greater chance of a chiropractor fucking you up and its a neck issue, would be a hard fuck no. There’s been repeated studies showing that chiropractor manipulation of the neck has a greater than acceptable chance of death, paralysis, stroke, and arterial dissections.
Order of operations
- PT and massage therapy
- A relevant specialist (you dont mention what issues you actually have) and this may lead to
- surgical intervention