AnyOldName3

@AnyOldName3@lemmy.world

• ⁨Comment⁩ on ⁨That's a whole lotta hydrogen!⁩ ⁨⁨7⁩ ⁨minutes⁩ ago⁩:

  But this guy says it, and he’s defined himself to be the sole authority, so that matters more than any number of biologists.

  Every argument they come up with has been refuted in past threads, and they just dismiss anything they disagree with as irrelevant, but treating tenuous sources like a supposed screenshot of Imane Khalif’s SRY test originating from an obscure site that’s never been republished by a mainstream one, even if they’d been calling for her to be barred from future tournaments based on no evidence so would love to vindicate their stance with test results.

  It’s not worth your time to engage with them in good faith.

• ⁨Comment⁩ on ⁨That's a whole lotta hydrogen!⁩ ⁨⁨19⁩ ⁨minutes⁩ ago⁩:

  This is far from the second time. They show up a lot.

• ⁨Comment⁩ on ⁨Helldivers 2 gets new stealth missions today, and its super-slimmed install size version is finally ready to take over⁩ ⁨⁨3⁩ ⁨days⁩ ago⁩:

  It’s not exactly a rootkit - if you just don’t agree to the UAC prompt while it’s installing, it’ll refuse to install rather than doing the thing that makes it definitionally a rootkit and managing to gain admin access without the user’s permission - but the game does still require kernel-level anti-cheat.

• ⁨Comment⁩ on ⁨Cyberpunk 2077 VR mod flatlines, after CD Projekt file DMCA strike and request its creator drop their paywall⁩ ⁨⁨5⁩ ⁨days⁩ ago⁩:

  Generally when you see people advocate for not having to pay for things like that, it’s because they want to do away with currency and the concept that a living is something that needs to be earned rather than something everyone gets as a basic right. Plenty of people make art, including games, without a profit motive, so it’s not unreasonable to think that enough games would be made if everyone had way more free time and games were all made for free.

• ⁨Comment⁩ on ⁨Fear that quantum computing is on the cusp of cracking cryptocurrency's encryption spurs a global investment firm to remove Bitcoin from recommendations⁩ ⁨⁨6⁩ ⁨days⁩ ago⁩:

  In theory, quantum computing should be faster once hardware that’s faster is available, and only if the problem you’re trying to solve is in BQP, which isn’t that much of what computers are used for. Progress has been slow, but continuous, so the gap between simulating a quantum computer and actually using one has been shrinking. In October last year, Google’s Willow chip was verified to have achieved quantum advantage, i.e. done something that could be checked externally faster than a classical computer could have. It was only 13,000x faster, and in one specific task, which isn’t really enough to change the world, but ten or twenty years ago it was still thought to be fairly plausible that the physics might not be right and even if the practical problems were solved, they still wouldn’t work.

  Even if quantum computers get ludicrously fast, they’re still not going to be especially common, and they’ll be a piece of specialised equipment, more like an electron microscope than a home PC. Most people just don’t need to do any stuff that’s in BQP, so don’t care if they can do it faster. If you’re a company, university or government body that needs to do one of the very specific things that will be faster, though, they’ll be indispensable.

• ⁨Comment⁩ on ⁨Priming and sealing a painted print⁩ ⁨⁨1⁩ ⁨week⁩ ago⁩:

  I’ve never actually needed primer to paint PLA unless the paint I was using was terrible, and wouldn’t have stuck to the primer very well, either. Tamiya’s acrylics have been entirely issue-free for me, both with a brush, or thinned and airbrushed, and they’re not that expensive, but I’ve also had acceptable results with random fifteen-year-old tubes of really cheap acrylics that were sold more as a children’s toy than a serious paint (although a lot of these tubes had gone bad in that time) and with Humbrol and Revel acrylics and enamels (although their acrylics come in pots that don’t seal very well, so it’s not that uncommon for them to be already cured when you first open them - if you’re buying liquid acrylics for model painting, Tamiya is a better choice).

• ⁨Comment⁩ on ⁨Should speakers hum when they're connected to a stereo, but the volume of is turned all the way down?⁩ ⁨⁨1⁩ ⁨week⁩ ago⁩:

  If the ferrite is filtering a hum you can hear, it’s also filtering parts of your music that you can hear because a ferrite just dampens a frequency range and can’t tell what is and isn’t supposed to be there.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  And the context was a sentence that was correct if you used OED sense 1, or MW sense 1, but you decided to parse it as MW sense 2b and then complain that the sentence was incorrect.

• ⁨Comment⁩ on ⁨Will the government be able to put 2 & 2 together⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  Obviously they’ll have a carve-out for businesses that apply for a VPN licence and have the other end of the VPN remain in the country. Not because they listen to the public saying that VPNs have legitimate uses, but because the megacorp they consult with before drafting the law says it’s the only legitimate use-case and has a VPN product they can sell to small businesses that can’t afford to wait for their self-hosted VPN to be certified by the one overworked civil servant who has sole responsibility for approving every VPN licence.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  OED:

  1. totally or partially resistant to a particular infectious disease or pathogen.
  2. protected or exempt, especially from an obligation or the effects of something.

  Merriam Webster

  1. : not susceptible or responsive especially: having a high degree of resistance to a disease
  2. a: produced by, involved in, or concerned with immunity or an immune response

  If you have a sample of HIV at 37°C in blood, but with all the immune cells removed, it’ll still all become inert after around a week simply due to chemical reactions with other components of blood etc… It’s pretty comparable to a population of animals - if you take away their ability to reproduce, they’ll die of old age when left for long enough even if you’re not actively killing them.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:
  • this is a shitpost community, not a biotech publication, so immune here means the dictionary definition, not any domain-specific technical jargon, otherwise people can’t make shitposts about diplomatic immunity
  • lacking the receptor that HIV uses to hijack the regular immune response in order to reproduce means the regular immune response destroys it
  • even in a normal person, after exposure, a lot of HIV gets destroyed by other parts of the immune system, often enough to eliminate it before an infection gains a foothold. Once an infection takes hold, it outbreeds the immune response as it’s the part best equipped to deal with a large viral load that it interferes with.
  • if you’ve got the virus in your body, but due to the lack of the receptor, it can’t reproduce, then it doesn’t remain viable for very long as each viron accumulates damage over time, and ceases to function once it’s too badly damaged. People carrying a disease have enough viral reproduction going on to balance out the virus being destroyed.
• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  Even if you ignore that there’s an entirely valid sense of the word immune that has nothing do do with biology (i.e. the one in phrases like diplomatic immunity), my original comment is entirely consistent with the dictionary definition of the biological sense of the word. There are probably sub-fields of biology where immunity is used as jargon for something much more specific than the dictionary definition, but this is lemmyshitpost, not a peer-reviewed domain-specific publication.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  When a normal person is exposed to HIV, it reproduces inside of them, so can then go on to expose more people, and if there’s enough of it, infect them in turn (if there’s a smaller amount, their immune system will normally be able to clean it up before it gets enough of a foothold). If someone’s lacking the receptor, then no matter how much they were exposed to, their immune system will eventually manage to remove it all without becoming infected because it can’t reproduce. If they had a ludicrously large viral load, then there’s a possibility that it could be passed on before it was destroyed, but most of the ways people get exposed to HIV aren’t enough to infect someone who’s vulnerable, let alone infect someone else via secondary exposure if there’s not been time for the infection to grow.

• ⁨Comment⁩ on ⁨[deleted]⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  The vast majority of NATO that isn’t the US is covered by the EU’s Mutual Defence Clause, so this kind of already exists. It sucks for the NATO members that aren’t in the EU, though, e.g. Greenland.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  People without the receptor that HIV targets are immune to HIV because of that, like how a rock is immune to verbal abuse or double foot amputees are immune to ingrown toenails. The immune system being able to kill something isn’t the only way things can be immune to other things.

• ⁨Comment⁩ on ⁨I tested putting my printsheet in the dishwasher⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  Enzymes are specific to a particular molecule, or class of molecules with a particular pattern. A PEI buildplate is not getting eaten by the proteases in a dishwasher tablet. The reasons you’re not supposed to rinse things before putting them in the dishwasher are:

  • most dishwashers have sensors to detect how much material is ending up in the water, and if things have been rinsed, it can mislead them into thinking the load is lighter than it really is.
  • dishwashers replace some of the dirty water part way through the load, and the enzymes are more soluble than the dirt, so if there’s not much food residue for them to stick to, they can end up getting rinsed away part way through the cycle.
  • it uses water and your time to rinse the dishes first, which is a waste if it doesn’t make them end up any cleaner.
• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  That tests the AIDS immunity, but not whether there are off-target edits. IIRC, the mothers were all HIV-positive, so the children are all pretty likely to be exposed anyway, which was part of how he justified the experiment to himself.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  If he got incredibly lucky, they’re immune to AIDS. It’s much more likely that they’re not and will develop symptoms of new and exciting genetic disorders never seen before.

  The biggest problem was that the technique used is really unreliable, so you’d expect off-target edits to be more common than on-target ones for a human-sized genome. For bacteria, you can get around it by letting the modified bacteria reproduce for a few generations, then testing most of them. If they’re all good, then it worked, and if any aren’t, you need to make a new batch. Testing DNA destroys the cells you’re testing, so if you test enough cells in a human embryo to be sure that the edits worked, it dies. You can’t just start when the embryo is a single cell to ensure that the whole thing’s been edited in the same way as you need to test something pre-edit to be able to detect off-target edits.

• ⁨Comment⁩ on ⁨Resin printing in the cold⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  I think it was pretty reasonable of them to worry - lots of people who don’t like spending unnecessary money also don’t like spending not-obviously-necessary money on safety equipment, and there’s plenty of material on the internet that would imply resin printing is completely safe as long as you don’t drink the stuff. Resin printing with woefully inadequate ventilation/PPE is really common, so it’s a pretty safe bet that anyone asking questions is probably also doing something unsafe without realising it, especially as resin not liking the cold is something a lot of people learn about fairly early on (unless they live somewhere where it never gets below 20°C).

• ⁨Comment⁩ on ⁨The most outlandish tech CEO quotes from 2025⁩ ⁨⁨3⁩ ⁨weeks⁩ ago⁩:

  To be fair, if I had all that money, I’d probably just pay someone to figure out how to make it do the most good, and continue spending at least some of my time shitposting. It’s okay to have hobbies, but it’s bad to hoard the money or invest it in evil.

• ⁨Comment⁩ on ⁨Seven Diabetes Patients Die Due to Undisclosed Bug in Abbott's Continuous Glucose Monitors⁩ ⁨⁨4⁩ ⁨weeks⁩ ago⁩:

  I’ve found this is really dependent on placement. If I put my libre a couple of centimeters away from the region I usually use, it’ll read low all night, but as long as I stick to the zone I’ve determined to be fine, it’ll agree with a blood test even if I’ve had pressure on it for ages. Also, the 3 is more forgiving than the 1 or 2 because it’s smaller than the older models, so affects how much the skin bends and squishes less.

• ⁨Comment⁩ on ⁨Teenage Jehovah's Witness can receive blood transfusion, judge rules⁩ ⁨⁨4⁩ ⁨weeks⁩ ago⁩:

  In the UK, if there’s a medical issue with any legal or ethical ambiguity, especially if a child is involved, doctors are required to defer the decision to a court. It means a lot of decisions end up being made by courts.

• ⁨Comment⁩ on ⁨Firefox Will Ship with an "AI Kill Switch" to Completely Disable all AI Features - 9to5Linux⁩ ⁨⁨4⁩ ⁨weeks⁩ ago⁩:

  It wouldn’t be Roku’s Baselisk if it didn’t do things that hurt.

• ⁨Comment⁩ on ⁨Day 517 of posting a Daily Screenshot from the games I've been playing⁩ ⁨⁨5⁩ ⁨weeks⁩ ago⁩:

  Obviously, most people don’t replace their TV every year, so it was years after new sales were mostly LCDs that most people had LCDs, but companies making content like to be sure it looks good with the latest screens.

• ⁨Comment⁩ on ⁨Day 517 of posting a Daily Screenshot from the games I've been playing⁩ ⁨⁨5⁩ ⁨weeks⁩ ago⁩:

  I think you might have misjudged when LCDs became common as by the end of 2004, when Halo 2 released, LCD TVs were already a reasonable fraction of new TV sales, and in parts of the world, it was only a few months later that LCD TVs became the majority. For PC monitors, the switch came earlier, so it was clear CRTs were on the way out while the game was being developed. If they hadn’t expected a significant number of players to use an LCD and tweaked the game as much as necessary to ensure that was fine, it would have been foolish

• ⁨Comment⁩ on ⁨Microcontroller recommendations for a weather station⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  Unless you’re making thousands of something, an ESP32 is cheap enough that it shouldn’t matter whether or not it’s overkill. Getting something simpler will only save you a few pennies unless you’re overspending as ESP32 breakout boards are available for less than £2.

  The power draw will be a problem, though, unless you disable WiFi. They’re not really button-cell-friendly.

• ⁨Comment⁩ on ⁨for a better future for ur children⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  There have been times it’s been used against a whole carful of people, and cars are bigger than seven inches.

• ⁨Comment⁩ on ⁨The phrase "edited it" is soo weird to pronounce⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  Much more straightforward in British English where d and t are more distinct

• ⁨Comment⁩ on ⁨The phrase "edited it" is soo weird to pronounce⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  I’m glad to see someone’s made this because it’s been bouncing around in my head for ages but I’ve never got around to putting it together and letting it out.

• ⁨Comment⁩ on ⁨same shit every day, on god⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  It’ll heat up the firebox, which is exactly what the firebox wants to happen. It’s not like we’re using precisely-timed explosives to briefly make the mass much more than critical and counter its desire to blow itself apart for long enough that it blows other things apart, too.