There is (according to the video) concrete evidence for both acute toxicity as well as causal carcinogenic effects when it comes to PFOA.
The distinction here is between lpng-chained Fluoropolymers like Teflon, which are completely benign as far as evidence suggests; and fluoroalkyl acids (like PFOA), that are short-chained, can enter the bloodstream, and mimic the structure of fatty acids thus being able to bond to stuff in our body.
pulsewidth@lemmy.world 1 day ago
“To poison” just means to make people ill by ingesting it. PFOAs are quite well studied and are known carcinogens, and definitely toxic according to multiple studies, this is trivial to find on Wikipedia, etc so… I dunno - seems like a contrarian take?
PFOA studies linking exposure to a number of health conditions, including thyroid disorders, chronic kidney disease, liver disease, testicular cancer, infertility and low birth weight. The list goes on, those are just some.
en.m.wikipedia.org/wiki/Perfluorooctanoic_acid#To…
pixxelkick@lemmy.world 16 hours ago
Its important to understand that “cannot be dismissed” is not the same as “we think it does do this”
It’s a double negative, its “we dont not think it causes it”, but waaaaay more study is needed.
Serum Concentrations of Per- and Polyfluoroalkyl Substances and Risk of Renal Cell Carcinoma
Actually is a new one for me, I havent seen this one, and it does look much more compelling than the other smaller studies, this one is more concerning than the others.Fourth link is a lot of nothing, why did you bother linking it? It just discusses other studies but doesnt add anything new of substance.
Fifth link is pretty sketchy, theres many other variables that also associate, and they didnt even find a link between specifically PFOS anyways
Its important to note that every single one of these studies is empirical post exposure which means many other associated variables can also contribute.
People with low PFAS vs high PFAS exposure almost undoubtedly are also exposed to many other things… like pollution in general
It’s borderline impossible to actually separate out PFAS levels from these other entangled variables, people who are heavily exposed to 1 type of pollution will also be exposed to many others, and theres a heavy association between living situation and PFAS exposure.
That is why its so damn hard to get any conclusive proof on this, the only way to truly figure it out would be to purposefully administer PFAS to people intentionally in a controlled environment, to try and separate out variables.
The relationships that do show up are all very tenuous, and could easily be also explained by the dozens of other variables, so thats why you keep seeing the wording of “may contribute” or “requires further study” or “associated with”
pulsewidth@lemmy.world 21 minutes ago
Your comment cherry picks the weakest language of the Wikipedia article and studies and ignores the rest. You’ll struggle to find any reputable study anywhere that says “our study proves that X does Y” like you’re asking, because thats not how studies language is conveyed and would be incorrect language to use in a medical study. When 20 studies all say “we have shown a strong correlation between cigarette consumption and cancer of the throat, mouth, and lungs” then you will hear scientists say “the link between cancer and cigarettes is known, and well studied” and news articles will say “cigarettes cause cancer”.
Your suggestion that the only way we’d know for sure is human trials of intentional PFOA exposure is… I’m gonna be generous and say… naieve. Scientists are perfectly fine with using lab, mouse, and emprical cross-sectional studies - that’s all valid scientific evidence. They don’t actually need to take the final Dr Mengele step of subjecting people directly to suspected toxins before they can already draw highly accurate conclusions, especially for something like PFOA that has large sections of the population with high dosages that they can compare against those with low dosages already.
Not true. Just one example, we have many population groups that live in areas where groundwater is used for drinking that also live near a firefighting training base/station that has released huge amounts of PFOAs into the aquifers. These populations are otherwise quite normally distributed for age/weight/health/occupation and exposure to other chemicals and perfect for study of PFOAs and have been shown in studies to have much higher levels in their blood serum.
It’s fine though - if you wanna sprikle PFOA on your cereal or something until 100 more studies are done, I can’t stop you. But just know that your tendency to cherry pick data and your unconventional assessment methods of studies is giving you a very poorly informed choice.