Anyone who knows me knows that I've been using next cloud forever, and I fully endorse anyone doing any level of self hosting should have their own. It's just a self-hosted Swiss army knife, and I personally find it even easier to use than something like SharePoint.

I had a recurring issue where my logs would show "MYSQL server has gone away". It generally wasn't doing anything, but occasionally would cause large large file uploads to fail or other random failures that would stop quickly after.

The only thing I did is I went in and doubled wait_timeout in my /etc/mysql/mariadb.conf.d/50-server.cnf

After that, my larger file uploads went through properly.

It might not be the best solution but it did work so I figured I'd share.