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Comment on NAC makes you insensitive to alcohol

BananaTrifleViolin@kbin.social ⁨1⁩ ⁨year⁩ ago

So big mistake here: NAC is not harmless. It does have side effects and it also has toxicity at high doses.

It has not been studied in long term use orally or IV, it's main use b omg paracetamol overdose treatment. Inhalation is more studied but it is not absorbed into the body on the same way.

We think it is safe but we haven't actually done human trials to be sure. What we have found in mine is that high doses can cause lung and heart damage and also when it comes to alcohol it is protective iif taken before alcohol consumption BUT amplifies the toxicity to the liver if about 4 hours taken after alcohol. All of this is summarised on the Wikipedia page which looks to be good quality.

Overall it may be a useful drug but don't take it off label or self medicating. Medicine is littered with unexpected effects of drugs that only came out once it was too late. Thalidomide is a good example - a "wonder drug" for nausea used in pregnancy that was not tested and caused horrific birth defects.

Your body is not a lab, be careful experimenting with supposedly "safe" drugs.

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livus@kbin.social ⁨1⁩ ⁨year⁩ ago
@BananaTrifleViolin

What we have found in mice is that high doses can cause lung and heart damage

NAC promotes cancerous tumour growth in mice, just FYI.

@kSPvhmTOlwvMd7Y7E

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- kSPvhmTOlwvMd7Y7E@lemmy.world ⁨1⁩ ⁨year⁩ ago
  Thank you, that’s an important note.
  
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HopeOfTheGunblade@kbin.social ⁨1⁩ ⁨year⁩ ago
Evident to end users. Thalidomide was well known to the makers to be godawful for pregnant people well before then - check out the behind the bastards episode on it.

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- Cruxifux@lemmy.world ⁨1⁩ ⁨year⁩ ago
  Are those the same dicks who made the fake breast milk that starved kids of nutrients or am I thinking of a The Dollop episode?
  
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  - intensely_human@lemm.ee ⁨1⁩ ⁨year⁩ ago
    That was Nestle wasn’t it? In Africa?
    
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    HopeOfTheGunblade@kbin.social ⁨1⁩ ⁨year⁩ ago
    Nestle gave free formula in Africa for long enough for the mothers to stop producing breast milk then charged for more, causing a bunch of starvation. Not sure if that's what Cruxifux meant.
    
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intensely_human@lemm.ee ⁨1⁩ ⁨year⁩ ago
What I use it for short term is removing middle aged smell.

Middle aged smell is the result of the skin’s antioxidant properties declining, so whenever I start getting middle age smell going, I take an NAC and the problem’s gone for a month or two.

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kSPvhmTOlwvMd7Y7E@lemmy.world ⁨1⁩ ⁨year⁩ ago
Yes, all good reminder here. You re right

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