First-in-human just means it’s the first time that specific therapy is being tested on humans instead of animals (e.g. mice, dogs, monkeys), and the primary objective of the trial is to test that it’s safe for use in humans. It doesn’t refer to the concept of gene editing or lowering cholesterol.
Comment on First-In-Human Trial Of CRISPR Gene-Editing Therapy Safely Lowered Cholesterol, Triglycerides
palordrolap@fedia.io 3 days ago
Is this the first human trial, or just the first officially sanctioned one?
IIRC there was that one guy who experimented on himself and cured his lactose intolerance.
... found it: https://www.youtube.com/watch?v=J3FcbFqSoQY
Nearly 8 years ago.
ClockworkOtter@lemmy.world 3 days ago
pound_heap@lemmy.dbzer0.com 2 days ago
was safe and reduced LDL cholesterol by nearly 50% and reduced triglycerides by about 55%
From the referenced article
ClockworkOtter@lemmy.world 2 days ago
What is the point of your comment?
Cort@lemmy.world 3 days ago
Thought emporium?
Yep thought emporium.
But I think the Chinese scientist that experimented on babies did it few years before that even.
offspec@lemmy.world 3 days ago
I feel obligated to mention that he doesn’t modify his own genes, he infects himself with a modified bacteria that produces lactase.
TonyTonyChopper@mander.xyz 3 days ago
you can just eat yogurt to get the same results
MIDItheKID@lemmy.world 2 days ago
Wait is that true? I would totally eat yogurt if it meant I could enjoy ice cream again.