Endorphin doesn’t cross the barrier but morphine does, we basically find ways to sneak stuff into the brain.
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viscacha@feddit.org 1 month agoHow do drugs work then? Many are structurally similar to serotonin and are pretty effective when ingested (psilocybin, LSD, …).
olafurp@lemmy.world 1 month ago
FLP22012005@lemmy.world 1 month ago
They, or products of these drugs, do cross the BBB, and stimulate the same (sub)receptors as serotonin or dopamine.