Endorphin doesn’t cross the barrier but morphine does, we basically find ways to sneak stuff into the brain.
Comment on [deleted]
viscacha@feddit.org 3 days agoHow do drugs work then? Many are structurally similar to serotonin and are pretty effective when ingested (psilocybin, LSD, …).
olafurp@lemmy.world 3 days ago
FLP22012005@lemmy.world 3 days ago
They, or products of these drugs, do cross the BBB, and stimulate the same (sub)receptors as serotonin or dopamine.