Comment on [deleted]
Novocirab@feddit.org 4 weeks ago
Gut health is important, but the serotonin and dopamine from there won’t ever cross the blood–brain barrier, so the effects of the gut on mental health (which are very real) are mediated through other things.
viscacha@feddit.org 4 weeks ago
How do drugs work then? Many are structurally similar to serotonin and are pretty effective when ingested (psilocybin, LSD, …).
FLP22012005@lemmy.world 4 weeks ago
They, or products of these drugs, do cross the BBB, and stimulate the same (sub)receptors as serotonin or dopamine.
olafurp@lemmy.world 4 weeks ago
Endorphin doesn’t cross the barrier but morphine does, we basically find ways to sneak stuff into the brain.