Yes and moreover, feeds work at the community level, not individual posts. Which is a step in the right direction but you may want finer-grain control. Filters may offer more what you are looking for in that case.

I did not mention previously but PieFed also allows you to block all users from a user-specified instance, without requiring admin approval to perform full defederation. It is not perfect but it is very good and e.g. I use it to block Lemmy.ml, which saves me a lot of headaches as most of the worst, most argumentative and unfriendly (and batshit insane) comments I've seen come from there. Lemmy's instance filter is horribly misnamed - it would have much better been called a community muting, as it blocks communities from that insurance but the users remain free to troll you in communities located in other instances, leaving replies, triggering notifications, etc.

The Lemmy apps Sync and Connect can also block all users from an instance.