Klipper will halt if a canbus toolhead disconnects anyhow, or at least how I have it configured it seems to, will handle packet loss just fine, outright disconnects? Nah, it wasn’t happy.

Klipper wise, imagine you could do something with the can uuid, I have a macro that I found that sets offset based on sheet (replicating prusa’s sheet selection in marlin, I like to have a bit less squish for nylon for example, more for textured sheets), offsets stored in a config file but you could easily swap that for an actual database if you wanted to.

There’s some klipper extensions like spoolman that are kinda sorta that for material management, yes relies on manual entry afaik, but supports material changes so presumably multi toolheads and more importantly, can share across printers, have it running on my server.

Don’t even get me going on patents…