MIT engineers solve the sticky-cell problem in bioreactors and other industries

Comments

• Xanthobilly@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

  You know what’s worse for bioprocessing than sticky cells? Bubbles.

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  • TropicalDingdong@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

    MIT is built on headlines.

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    • Xanthobilly@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Ain’t that the truth.

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  • hamsterkill@lemmy.sdf.org ⁨3⁩ ⁨weeks⁩ ago

    The article does mention this problem and they claim to have been able to pull it off somehow.

    “Mammalian cells are orders of magnitude more sensitive than algae cells, but even with those cells, we were able to detach them with no impact to the viability of the cell,” Vandereydt says.

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  • rigatti@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

    What happens when they interact with bubbles?

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    • Xanthobilly@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Bubbles act as a water/air interface. The lipid membrane of a cell is a wall that has an internal hydrophobic layer made of phospholipids. Phospholipids when introduced to a water/air interface orient their hydrophobic side into the air, away from water. In other words the bubble rips the cell membrane apart by pulling phospholipids out of the membrane.

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