[Solved - I was blind. I had to enable local access and disable DNS Switch mode in Eddie]
I wanted to edit main post, but fatfingered delete button… Solved in meantime, but reposting just because of that, sorry about that…
I couldn’t access local services running on home server (not exposed) while VPN connection is active (Eddie). Fellow selfhoster told me to check if I have enabled local network, then I also found settings where I had to disable DNS Switch mode which is solution! Thank you