Yeah, a good enclosure will have accoustically isolated drives (rubber bumpers at the drive mount points)

I run rack-mount servers, so drive noise is the least of my issues (fans are always the loudest part of any server) but I used to run in a Nanoxia DeepSilence 6 tower, and it was amazing. 1mm thick superstructure, insulation, accustically isolated drive mounts, etc. Couldn’t hear that even when the fans were running at full steam.