I’m excited to introduce you to this if you haven’t seen it!

teachingtechyt.github.io/calibration.html

I use this as a general guide for every time I buy a new material, manufacturer, and/or color of filament. There’s YouTube videos explaining everything every step of the way.

For a new printer (or significant modifications) I’d go through the whole thing. For new filament, if I haven’t used it before, I do flow calibration, temperature tuning, retraction tuning, pressure/linear advance tuning, and max flow tuning, not necessarily in that order. I’ve found that as I’ve learned and experimented more I’ve branched out into more esoteric tools for some things.

My filament printer is a fairly heavily modified ender 3 pro (spider hotend, direct drive, dual z axis, spring steel bed, solid bed spacers, herome gen 7 cooler, cr touch, stepper driver diodes, and an adxl345 waiting for me to mount and wire it… I think that’s it). So I’m not saying this as a Creality hater, I love my ender, I hate their software and firmware. I had a terrible time with their Marlin firmware and ended up building it myself. I’ve since switched to klipper though and highly recommend it, it got me a reasonable quality benchy in around 30 minutes.

My point there is that I have had a hard time with the default profiles across the board, even before the mods. For filament printing I use Prusaslicer, though I do like Superslicer and Orcaslicer seems nice as well, I just have all my profiles built for Prusaslicer and it generally just works.