I would suggest removing the nozzle, and clearing it if there’s a jam first, then seating the heat block to the break. Then the nozzle. Both the best break and the nozzle need to be hot as you’re doing the final tightening. I don’t know that the order really matters … it’s just how i do it. I do recommend being systematic about how you go through things. It’s helpful to have a process.

Systematic processes help you to not forget things, like forgetting to reconnect the BLtouch cable when doing stuff with the hot end. (Ooops.)