Two main things are Lightroom and Maschine.

I know about Darktable. And lots of others. The photo editing application is the easy part - lots of options. The lightroom secret sauce is fully integrated workflow with mobile and desktop. I am content to pay money for this as it deserves to cost money. However, Adobe does not play nicely with Linux. For this use case, I could likely dual boot (or virtual box).

Music production is a challenge though. Dual booting isn’t an option as it’s my main use case. Maschine (the HW) doesn’t run on Linux. Yes, I know someone a few years ago wrote a partially functional driver for a previous incarnation of the HW, that works in midi mode, but that’s not how I use it. Paid good money for it - not keen on burning it.

I even considered running it in a box (assuming can pass through the usb), but as I started to tally up the dependencies, I would come close to having to put it all on the vbox, ending up with a setup that could only be appreciated by the most zealous Rube Goldberg afficionado…

On the software side, I can likely get wrappers to run a lot of it, but it’s an ongoing dice roll. The DAW is easy (Reaper). But I have a bunch of stuff I use constantly that I paid for and I don’t want the OS to work against me. (And I want to be able to hold the vendors’ feet to the feet when things don’t work properly - I’ve had support concerns (for legit bugs) that fell on deaf ears when I said I use Reaper, which was not officially supported by a certain vendor. How much luck would I have with Linux?

Then there’s the audio interface. Yes - it’ll probably run. But it’s certainly not supported.

Unless vendors actually start supporting Linux (flatpaks/snappaks/whatever would be just dandy), running Linux remains an obstacle, not a solution. However, they won’t start supporting until user base grows. Chicken. Egg. Ugh.

It’s most unfortunate - I definitely try to kick tires on it to see if it’s feasible every few years, but I continue to hit a wall.

In the meantime, I, and, I hope others will keep pressure up on vendors whenever possible.