Just note unlike the other souls game enemies in 2 can permanently despawn after killing them multiple times.

The workaround is you can join the Company of Champions back in Majula, It’s the Alter up a hill to the right of the path that takes you to Heide’s Tower. It’s make enemies always respawn at the cost of them doing 50% more damage. Luckily the hand creatures are weak to fire and the puddles of oil they hide in can be lit up using fire arrows or bombs.