Thanks!
reddit.com/…/what_are_your_thoughts_on_subtlecryp…
Tldr; I had that question before myself. It doesn’t seem to introduce any improvement over WebCrypto API which itself should have gone through peer-review and auditing. (“Choose your browser wisely” could be considered the advice here.)
I’d like to still look into wasm for several other details of the project, but it seems the built-in browser cryptography functions are performant and generally pretty good if used correctly.