I usually don’t mind enemies having more health or taking less damage, but there’s gotta be a limit, and 6x is definitely far, far above that limit. Oblivion Remastered in particular was funny, because the damage multipliers only affect you. Meaning your followers or summons deal and take normal damage from enemies. If your sword feels like a wet noodle but your allies are doing just fine, something’s wrong. The difficulty sliders in that game were just poorly designed.

I think I eventually swapped to whatever setting is right above 1x damage taken/dealt. Fights were a bit too easy imo, but at least every mud crab wasn’t practically a miniboss.