I find asymmetrical sticks more comfortable to use. The natural position of my thumbs is in the top corners of the controller. Since the D-pad is rarely used, the left thumb stays in that sweet spot and the right jumps between the stick and the buttons.

I use a DS4 on my desktop, an Xbox 360 controller on my retropie box, and a Nintendo Pro controller on my Switch, and the DS4 is way less comfy than the other two. I only use the DS4 because it had better compatibility with Linux and other features (mostly gyro) when I shopped for one when I moved the Xbox controller to another room.

I’ve considered buying the DS5, but would much rather wait for something better, like a new Xbox controller with a gyro.