yea your memory b-cells are the one that maintains at a low levels of antibodies against certain disease, it is one of the reasons measles is dangerous they damage the dendritic cells which presents antigens to b-cells so your bascially partially immunosuppressed, besides the acute infection.
Comment on LPT: Go get a shot, now.
CubitOom@infosec.pub 2 days ago
So if one already had a dose of the previous booster about a year or so ago, would it be helpful to get the same version of the booster again now?
Is the post simply suggesting to people that haven’t yet had the booster go get it? Or is it saying you’re better off getting the same booster again rather than nothing?
Also, I’m assuming people with the means to go to a different country without these laughing stock “leaders” would be better waiting for those countries to approve and release up-to-date vaccines.
Tollana1234567@lemmy.today 2 days ago
egerlach@lemmy.ca 2 days ago
My understanding is that because of the type of protien that it encodes for, the immunity imparted by the vaccine decreases over time (because of complex immune system reasons). Never to 0%, but lower. The annual booster not only prepares you better for oncoming strains (in theory, when the vaccine research, development, and approval systems work as expected), but re-ups your immunity to existing strains.
The theory as I understand it is that because viruses like COVID-19 pass through populations in waves, your body is developing a very strong short-term immunity to neutralize any immediate “rebound” waves (imagine a wave bouncing off the side of a pool, yes, viruses move through populations like that). It then maintains a weaker, long-term response. By fooling your immune system into thinking you have COVID-19 right now, the vaccine bumps your body ino “short-term” response mode, so your best possible immune response is at the ready if the real thing shows up.
I am not an epidimeologist, but I read a lot of their work from 2020-2023. I might have details wrong, but if it’s been >6mo since you’ve had a booster, you would probably benefit from getting another one.
GrumpyDuckling@sh.itjust.works 2 days ago
Virus waves are exacerbated by holiday schedules. First school starts and kids are a massive disease vector. Then Thanksgiving comes and people spread it to their families and bring it back home. Then it has a month to spread and then Christmas comes.
Tollana1234567@lemmy.today 2 days ago
also people staying in doors during cold weather increases the infeciton rate.