Depends. You’re in luck, as someone made a DWQ (which is the most optimal way to run it, and should work in LM Studio): huggingface.co/mlx-community/…/main

It’s chonky though. The weights alone are like 40GB, so assume 50GB of VRAM allocation for some context. I’m not sure what Macs that equates to… 96GB? Can the 64GB can allocate enough?

Otherwise, the requirement is basically a 5090. You can stuff it into 32GB as an exl3.

Note that it is going to be slow on Macs, being a dense 72B model.