Yeah, this is an option on YouTube.

On Odysee, there’s both the option to “Block” channels, or seperately “Mute” channels. You can also manage your blocked and muted channels separately under Profile > Settings > Content Settings > Blocked and muted channels. According to this page in the official Help Hub:

Blocking: “When you block a user, the blocked user can no longer comment on any of your content, channel, or comment threads. In addition to this, all comments and reactions left by the blocked user on your content, channel, or in the comments section, will be filtered for everyone.”

Muting: “When you mute a user, you will no longer see them in any comment sections, replies, search results, homepage, related content, or anywhere else. They’re hidden from your experience on Odysee.”

So basically, if you don’t want to see their content (including comments); mute them. If you don’t want them to talk to you or be seen in your own channels’ comment sections by both yourself or others; block them. If you want absolutely nothing to do with them, you can both block and mute them simultaneously. Note: The article shows how to block/mute them from within the comments section. You can also block/mute them from the channel page itself or by clicking the 3-dots beside their video thumnail.