Alternatively, you can create new users from the command line.
This can be done as follows:

If synapse was installed via pip, activate the virtualenv as follows (if Synapse was installed via a prebuilt package, register_new_matrix_user should already be on the search path):

cd ~/synapse
source env/bin/activate
synctl start # if not already running
Run the following command:
register_new_matrix_user -c homeserver.yaml
This will prompt you to add details for the new user, and will then connect to the running Synapse to create the new user. For example:

New user localpart: erikj
Password:
Confirm password:
Make admin [no]:
Success!

This process uses a setting registration_shared_secret, which is shared between Synapse itself and the register_new_matrix_user script.
It doesn’t matter what it is (a random value is generated by --generate-config), but it should be kept secret, as anyone with knowledge of it can register users, including admin accounts, on your server even if enable_registration is false.

element-hq.github.io/synapse/…/installation.html