Yeah I’ve been on bupropion for about 1.5 years. Had an increased heart rate in the beginning as well so we started at a very low dosis, then went up step by step. However the side effects vanished after 2 months. I don’t feel hyper active, I just don’t feel super low anymore. It doesn’t make the depression go away but it allows me to work on it, because otherwise I couldn’t even get out of bed