Comment on Why does incest result in birth defects?

<- View Parent
AmidFuror@kbin.social ⁨9⁩ ⁨months⁩ ago

You're on the right track, and others have explained it. Mutations happen regardless. The important thing is that because of redundancy between two copies, the effects of many mutations can be masked. The mutated alleles circulate throughout the population and only face selection when combined with another loss-of-function allele in the same functional unit (gene).

Those recessive mutations are more likely to be matched with an identical partner allele if you reproduce with close relatives. Even if you don't do that, the odds are higher if you're in a closed community.

source
Sort:hotnewtop