The G502 has a thumbplatform, so that’s where my thumb goes. My pinky can’t touch the mouse cause my ring finger is in the way. But its slightly tilted, so its not exactly a horizontal mouse. Not nearly as vertical as this though. I just move it via the top of my palm. A vertical mouse seems like it would be uncomfortable in my right hand but fine with my left (maybe related to mixed handedness, maybe related to the different ways my wrists healed after breaking).