Big difference for me between the RPi 5 and orange pi 5 Plus is more RAM and m.2 NVME support on board. It also has four additional efficiency cores and dual 2.5G NICs, but that’s less important to me.

Downside is it has a less polished ecosystem.

Overall though I’ve been happy! But I also love my collection of raspberry pis, so it’s a matter of taste I guess.