I haven't seen all of Discovery, Enterprise, or DS9 so I'm completely unqualified to participate in this, but I'll make a write-in vote for Original-flavor T'Pring. Biiiiiiiishhhhhhh

SNW T'Pring though, I love her. She's got actual depth and I can empathize with her.

Runner-up: TOS T'Pau. Stuck-up xenophobe, plus they gave her that dumb early modern English dialogue of thees and thous that was supposed to convey ancient wisdom or something but they conjugated it all wrong and it's annoying as hell