Comment on Crispr gene editing shown to permanently lower hereditary high cholesterol
Kethal@lemmy.world 7 months agoRestriction enzymes cut at specific sequences, and although there are lots of variations, this restricts where the new material can be inserted. CRISPR can match an arbitrary sequence, so there is much more control over where changes are made.
j4yt33@feddit.de 7 months ago
Yes, although it’s not completely arbitrary as you need a PAM sequence to be present right where you want to cut the DNA. It’s quite small though so chances are, you’ll find one in a convenient location