Nukes are becoming a problem, because China is ramping up production. It will be just natural for India to do the same. From a two-way MAD situation, we’re getting into a 4-way Mexican standoff. That’s… really bad.
There won’t be an “AI insurgency”, just enough people plugging in plugs for some dumb AIs to tell them they can win the standoff. Let’s hope they don’t also put AIs in charge of the multiple nuclear launch buttons… or let the people in charge check with their own, like on a smartphone, dumb AI telling them to go ahead.
Climate change is clearly a done thing, unless we get something like unlimited fusion power to start some terraforming projects (seems unlikely).
You have a point with insects, but I think that’s just linked to climate change; populations will migrate wherever they get something to eat, even if that turns out to be Antarctica.