For this kind of study, we are really not that much different from mice.

We share 97.5% of our DNA with mice. We share many similarities in our immune systems, brain, and yes even gut.

The study uses mice to try and find a mechanism of ageing in humans, and they test their theories on mice. They do find a mechanism! It is rather unlikely that the mechanism they find does not apply at all in humans.

If we didn’t use animal models to try and understand human biology our models, medicine, drugs, etc would be far far worse.

For example see: blood.ca/…/why-do-scientists-use-mice-medical