I’ve only had one exposure with a multi-head printer, and it was incredibly messy. No matter what settings I used, there ended up being drips from the unused nozzle.

My most recent printer is an Anycubic Kobra Max 3, and I’d take the wasted filament over the sloppy prints any day. It’s a bed slinger, so maybe not what you had in mind, but they do make one with an enclosure.