If you’ve got that experience under your belt, you’ll be just fine. I haven’t tackled zfs myself yet (I’m lacking the RAM, plus I was put off by the ECC RAM recommendation). But I know it unifies a lot of the things you’re already familiar with under one roof (volume management and journaling) and adds more cool features (snapshotting, RAID, encryption) without you having to combine and manage several different technologies (mdadm for RAID, LVM, LUKS, …). I did that on my main rig and it turned out to be rather complex. Hence the switch to btrfs to at least squash a bit of complexity.