I have both running right now. Mint on my laptop and media server. Debian only because it was previously required for Home Assistant support, (support which they’ve now dropped.)

Both distros are extraordinarily reliable, but I much prefer Mint. Debian is more focused on security and some of the design choices focus on that over usability. My LAN is completely locked down and only accessible via Wireguard so IDK how much better security it provides in my situation. Mint has every package I’ve ever needed prebuilt while I have had to build some packages for Debian.

Bottom line: For me there is no real reason to switch from Debian to Mint or visa-versa, but if I were installing from scratch I’d choose Mint every time.