Thanks for chiming in, but I’m not sure I understand the implications. It’s not trustworthy ? I shouldn’t listen to the conclusions ?
Comment on Tattoo Ink Moves Through the Body, Killing Immune Cells and Weakening Vaccine Response
SinAdjetivos@lemmy.world 1 week ago
The full paper is here and, as usual, it’s hardly anything and decontextualized in order to get a publishable result.
This one is so bad that it doesn’t use established baselines or do any form of statistical analysis on the results instead opting for their own “baseline” measurements using very small sample sizes. It also plays a smoke and mirrors game where it shows a result for short term immunological response and then uses that to insinuate the ‘slightly reduced but still likely well within the error of the poor control’ long term effects are worth noting.
Other major flaws:
- As others have mentioned, mice are a terrible model for this as their skin is very thin and proper tattooing is near impossible.
- They mention verifying with human cadavers but don’t include any data from those.
- There was no control group, the baseline was an untreated mouse, not one with an acute foot trauma.
- Mice age very quickly, best I can tell the immunological markers weren’t age controlled. 2 months out of a <2 year lifespan is a lot of aging. Again, if there was a proper control to measure against.
- The obsfucation of the raw data into cheesy and unreadable box and whisker plots is hella suspicious.
At best it’s a very poorly communicated and poorly designed experiment but I suspect that’s due to it result hunting.
Hadriscus@jlai.lu 1 week ago
SinAdjetivos@lemmy.world 1 week ago
The implications are the variables are conflated and the conclusions are overblown.
It should come as no surprise that acute trauma and injecting a foreign substance would cause a relatively significant immunological response. The issue is that for the “chronic phase”, which is where the novelty of this research lies, the evidence shown is far from difinitive compared to the story being told and what results are shown aren’t overly significant.
Even if you 100% believe the paper the conclusion is that the effect of getting tattooed is, arguably, similar to catching the flu once. However, the paper itself tried to obfuscate that so they have a more impactful result and the marketing/outreach/media site that was linked here doubles down on it trying to sell the story of “tattoos==illness and death”!!!
Hadriscus@jlai.lu 1 week ago
Ok, I understand. Thanks for providing clarity
p03locke@lemmy.dbzer0.com 1 week ago
What the hell? Was this even peer reviewed?
P1nkman@lemmy.world 1 week ago
Probably by LLMs.
SinAdjetivos@lemmy.world 1 week ago
Oh honey… This is barely below average.