I run all critical services like PiHole, Homebridge and Loxberry on separate Pi machines, a Pi Zero 2 for apps I need to have 24/7 like Portainer and Heimdall. My main server is a Dell which serves Jellyfin, Immich and other stuff. All servers back up their data on my NAS, which itself is doing a nightly backup on a dedicated HDD. I need to have an out-of-home backup yet, but comes time comes money.