I recently set up the whole stack (Postfix, Dovecot, OpenDKIM) on a VPS. I wanted to do it from home, but my ISP won’t provide a static IP or open ports 25/465/587 for consumer customers, no exceptions.

It took me about two days to get everything working, but most of that was because I went in with very little knowledge of how email even actually works. If you’re looking for a learning experience, I’d say go for it. If you just want a working email setup quickly, I wouldn’t recommend it.

I haven’t noticed any deliverability issues so far. Just make sure you have SPF, DKIM, DMARC, and PTR records all set correctly from the start.