The choice of character, kart and tires matter a lot actually. The choice of glider matters a little.

If you’re somewhat good at drifting and getting stunts, maxing acceleration and handling over any other stat (which you can see in the kart selection menu, when you press + or -) is the way to go. My standard setup is yoshi + the bug car + roller tires + parachute. I think there are technically a few karts that are ever so slightly better but I‘m to vain to use them.