I think I’ve seen software swaps for the actual presses in most situations where I’d be able to.

I think the only time I consider doing something is when I’m playing a Nintendo game on non Nintendo hardware, so my MiSTer or on retroarch and both support swapping Nintendo to western style. If I’m holding a Nintendo controller, muscle memory makes it not really a problem for me at least

If you mean the actual physical buttons, I’d just say blank buttons are better than labelled ones in general, most popular controllers have blank mods that are pretty easy to do if you have a screwdriver with the appropriate bit.