I use Cura and a flash drive with my newer printer. But with my old printer that required being tethered (a Solidoodle2 from 2012) I was using MatterControl, as it was much easier and more reliable than Pronterface which came with the printer.

Though, the old PC I was using struggled when I did anything else on it while it was running the printer. The print speed would actually slow down or occasionally stop when loading a heavy webpage in a browser, for example.