You can do single-blind. You do prep, anesthetize, then open the card that decides if the surgery continues, or if the patient is simply awakened at the expected time.

You can also do it for surgeries that use locals, but then the surgical staff has to do a lot of miming/acting instead of actual cutting.

Medlife Crisis did a could of Placebo effect videos, and mentioned that he participated in a single-blind stent study.

I don’t know how you’d do double-blind.