They were never defeated.

When you say “defeated”, what exactly do you mean? You mean that they should cease to exist to be considered as such? If that’s the case then I would say it’s an unrealistic expectation.

I would say that they’ve been largely contained. If I remember correctly, back in the '50s almost half of the American population used to smoke. The percentage of people smoking has been consistently decreasing over the years thanks to regulation and increased taxation. Tobacco companies are definetly not as influential as they once were.