After a certain point, I’d imagine that there are diminishing effects. The difference between 100ug and 200ug is huge, but the difference between 1100ug and 1200ug isn’t anywhere near as big. After a certain point, it all just becomes a trip. But the size of the trip is entirely up to your mindset and individual brain chemistry; I know people who have found or lost religion on 300ug, and others who said 1500 was just a nice smooth trip.